1.
Chem Commun (Camb)
; 60(28): 3810-3813, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38488056
RESUMO
A novel probe C1 combining benzothiazole with a spiropyran section was developed for the specific detection of human serum albumin (HSA). The molecular docking suggested that the sulphonic acid group modification allowed C1 to form specific hydrogen bonds with lysine (Lys137) at fatty acid site 1 (FA1) of HSA, thus enabling fluorescence differentiation between HSA and BSA.
Assuntos
Soroalbumina Bovina , Albumina Sérica Humana , Humanos , Albumina Sérica Humana/química , Soroalbumina Bovina/química , Corantes Fluorescentes/química , Simulação de Acoplamento Molecular , Ácidos Graxos , Espectrometria de Fluorescência , Ligação Proteica
2.
Chem Commun (Camb)
; 56(57): 7925-7928, 2020 Jul 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32529994
RESUMO
In situ self-assembled boronate ester comprising commercially available 2-formylphenylboronic acid and 2-(2',3'-bihydroxyphenyl)benzothiazole (BHBT) is explored for the detection of ONOO- with product-boosted fluorescence. The self-assembly can detect ONOO- in the endoplasmic reticulum of living cells.