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Pharmacoepidemiol Drug Saf ; 18(10): 891-9, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19634117

RESUMO

PURPOSE: To evaluate the use of lipid-lowering treatment (LLT) among patients at risk for cardiovascular disease (CVD) in the US Military Health System (MHS). METHODS: The study examined healthcare service and prescription records among beneficiaries > or =18 years for calendar years 2002, 2004, and 2006. Patients were categorized based on cardiovascular (CV) risk, with exposure to LLT defined as one or more prescriptions for lipid-lowering medication. Logistic regression models estimated odds of treatment in 2004 and 2006 relative to 2002 after adjustment for age, gender, and CV risk. RESULTS: The yearly unadjusted population prevalence of LLT increased from 9.3% in 2002 to 14.7% in 2006. Among subjects with the highest CV risk, established coronary artery disease (CAD) or peripheral vascular disease (PVD), those receiving LLT increased from 55% in 2002 to 65% in 2006 (adjusted OR = 1.50, 95% CI 1.48, 1.52, p < 0.00). Treatment rates among diabetic patients with no coded CAD or PVD showed the largest relative increase from 47% in 2002 to 66% in 2006 (adjusted OR = 2.30, 95% CI 2.26, 2.332, p < 0.00). LLT growth was lowest among those with only 1 coded CV risk factor (adjusted OR = 1.32, 95% CI 1.31, 1.34, p < 0.00). CONCLUSIONS: The MHS experienced a significant increase in LLT among patients at greatest risk for cardiovascular disease. However, treatment may still be underutilized as approximately one-third of high-risk patients did not receive lipid-lowering medication.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Dislipidemias/tratamento farmacológico , Hipolipemiantes/uso terapêutico , Seguro Saúde , Medicina Militar , Padrões de Prática Médica , Adolescente , Adulto , Doenças Cardiovasculares/etiologia , Prescrições de Medicamentos , Uso de Medicamentos , Dislipidemias/complicações , Feminino , Fidelidade a Diretrizes , Humanos , Seguro Saúde/estatística & dados numéricos , Seguro de Serviços Farmacêuticos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Medicina Militar/estatística & dados numéricos , Razão de Chances , Vigilância da População , Guias de Prática Clínica como Assunto , Padrões de Prática Médica/estatística & dados numéricos , Medição de Risco , Fatores de Risco , Fatores de Tempo , Estados Unidos , Adulto Jovem
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