RESUMO
WHO recommends surveillance program for monitoring antibiotic resistance. The present study is a step in this direction. More than 100 clinical isolates of Staphylococcus aureus were collected from different hospitals in Karachi and in vitro studies were carried out by Agar dilution method using different generation of cephalosporins. The result showed high resistance to majority of these antibiotics with increase in the MIC's while only ceftriaxone and ceftazidime were the most potent one showing significant antimicrobial activity. For the detection of beta-lactamase iodometric method was used which showed that 80% strains produced beta-lactamase which clearly depict the misuse of these agents.
RESUMO
In the present study some herbal extracts have been tested for their antibacterial activity using seven different strains of Gram positive and Gram negative bacteria to measure the zone of inhibition. Extracts were found devoid of activity against all the microorganisms.
RESUMO
During present study hundred clinical isolates from cases of ear infection were tested from local population for resistance pattern, using eleven different antibiotics. A considerable percentage of isolates causing ear infection was resistant to number of antimicrobial drugs. The percentages of organisms isolated from ear infection are Pseudomonas aeruginosa (50%), Proteus species (16%), Staphylococcus aureus (15%), Klebsiella species (13%) and Escherichia coli (6%).
RESUMO
Ten samples of crude and processed honey were used to determine antimicrobial activity against twenty five species of pathogenic and nonpathogenic bacteria, commonly encountered in human infections. The antifungal activity was checked against ten parasitic and saprophytic fungi. Most of the samples of honey used in the study showed broad spectrum antibacterial and promising antifungal activity.
