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Int J Radiat Oncol Biol Phys ; 56(3): 690-6, 2003 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-12788174

RESUMO

PURPOSE: To evaluate the variability in catheter length, geometry, and dosimetric parameters of radical intraoperative high-dose-rate breasts implant during 7-11 days. METHODS AND MATERIALS: Simulator X-rays, CT scans, and dosimetric studies were repeated on alternate days in 14 consecutive patients treated with radical intraoperative two- or three-plane nylon catheter high-dose-rate implant (34 Gy in 10 fractions within 5 days). RESULTS: Significant variation was found in catheter length, but no major change was noted in implant geometry, homogeneity, or inhomogeneity indexes. A variation in length of >5 mm in one or more catheters was seen in all patients and >10 mm in 11 patients at any time during the implant. Of the 171 catheters in 14 patients, 100 (58%) and 38 (22%) showed a variation of >5 mm or >10 mm, respectively. The variation of >10 mm was reduced from 32% of catheters in the first 5 patients to 17% in the subsequent 9 patients (p = 0.028). Rigid catheter fixation might reduce length variation but may cause skin necrosis if the expanding cavity indents the skin for a long period against the fixation device. A dose homogeneity index of 0.90 (range 0.85-0.92) and dose nonuniformity ratio of 0.20 (range 0.12-0.25) were satisfactory. CONCLUSION: The catheter fixation and exit catheter length should be measured daily and if the implant is in situ for more than a few days, orthogonal X-rays and, if indicated, dosimetry should be repeated at least once.


Assuntos
Braquiterapia/métodos , Neoplasias da Mama/radioterapia , Radioisótopos de Irídio/uso terapêutico , Adulto , Idoso , Braquiterapia/instrumentação , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Desenho de Equipamento , Estudos de Viabilidade , Feminino , Humanos , Mastectomia Segmentar/métodos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Controle de Qualidade , Dosagem Radioterapêutica
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