1.
Extra amino group-containing gramicidin S analogs possessing outer membrane-permeabilizing activity.
Chem Commun (Camb)
; (11): 1264-5, 2003 Jun 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12809222
RESUMO
Novel (2S,4R)- and (2S,4S)-4-aminoproline residue-containing analogs of the cyclic decapeptide antibiotic gramicidin S were synthesized, which exhibited marked permeabilizing activity on the outer membrane of gram-negative bacteria.