RESUMO
PURPOSE: To compare the microbial flora, alkaline phosphatase (ALP) and interleukin-8 (IL-8) levels during orthodontic treatment with self-ligating brackets versus conventional brackets. PATIENTS AND METHODS: Forty patients were included in this study and distributed equally between two groups. One group received conventional edgewise brackets while the other group received DAMON self-ligating brackets. Periodontal parameters were recorded and biochemical and microbial analyses were conducted before bonding (baseline), and 14, 30, and 45 days after bonding. Paired t-test was performed to estimate the intergroup differences from the baseline at the various time points; unpaired t-test was used for intragroup comparisons. RESULTS: A significantly higher prevalence of gram-negative as well as gram-positive microorganisms was found in the group with conventional brackets than that with self-ligating brackets. Alkaline phosphatase (ALP) activity and interleukin-8 (IL-8) levels were significantly higher in the gingival crevicular fluid of the group with conventional brackets than that with self-ligating brackets. CONCLUSION: The conventional bracket-ligature technique exhibited an increase in IL-8 levels, ALP activity, and microbial colonization compared with that of the self-ligature technique. Accordingly, self-ligating brackets are recommended in orthodontic patients to improve periodontal health and minimize damage outcomes of periodontal tissue interventions.
RESUMO
AIM: To evaluate the effects of LLL on IL-6 levels in the GCF and the Probing Pocket Depth measurements (PPD) during orthodontic tooth movement in periodontally affected rabbits. METHODS: Twenty-four rabbits were divided into 3 groups: Group 1(G1), healthy rabbits with orthodontic movement, Group 2(G2) periodontally affected rabbits and orthodontic movement, Group 3(G3) periodontally affected rabbits with orthodontic movement and LLL therapy. A 0.014 stainless steel spring was inserted in the upper central incisors to produce 60gm force. Laser CAT 500 was applied for 3min/day for 2 weeks. PPD measurements were obtained at base line and after 14 days with electronic periodontal probe. RESULTS: IL-6 levels increased gradually after application of orthodontic force, afterwards the 8th day, a significant difference in the Il-6 levels between G1 vs. G2 and G2 vs. G3 was observed. PPD measurements showed significant difference between the three groups at base line and after 14 days. CLINICAL SIGNIFICANCE: LLL application can enhance periodontal ligament regeneration and decrease the periodontal tissue destruction through suppression of IL-6 levels.
