1.
Org Lett
; 16(17): 4590-3, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25156193
RESUMO
Azide and phosphoramidite functions were found to be compatible within one molecule and stable for months in solution kept frozen at -20 °C. An azide-carrying phosphoramidite was used for direct introduction of multiple azide modifications into synthetic oligonucleotides. A series of azide-containing oligonucleotides were modified further using click reactions with alkynes.