Desarrollo de glomerulopatía C3 en paciente con lipodistrofia parcial adquirida / Development of C3 glomerulopathy in a patient with acquired partial lipodistrophy

No disponible

Proteinuria masiva por nefropatía por cambios mínimos secundaria a tratamiento con D-penicilamina en un paciente con enfermedad de Wilson hepática. A propósito de un caso / Massive proteinuria for minimal change nephropathy secondary to treatment with D-penicilamine in a patient with Wilson's disease. Case report

No disponible

Vasculitis p-ANCA (+) autolimitada en paciente con preeclampsia / Self-limiting p-ANCA positive vasculitis in patient with pre-eclampsia

No disponible

Aplasia medular en paciente con nefropatía lúpica terminal y c-ANCA (+) / Medullary aplasia in c-ANCA positive patient with end-stage lupus nephritis

No disponible

Successful use of tocilizumab in a patient with nephrotic syndrome due to a rapidly progressing AA amyloidosis secondary to latent tuberculosis.

AA (secondary) amyloidosis is one of the most severe and uncommon complications of several rheumatic disorders and chronic infections such as tuberculosis (TB). Successful treatment depends on the control of the underlying inflammatory process, what can lead to an improvement or a regression in organ dysfunction. If the disorder persists, it has been reported in some cases of AA amyloidosis secondary to rheumatic diseases, that the use of biologic therapy is so far the only opportunity to reduce the development of AA amyloidosis and to reverse established deposits. We report herein a case of a latent TB infection complicated by a life-threatening AA amyloidosis presented as nephrotic syndrome. After an adequate antituberculostatic treatment, AA amyloidosis remained active and Tocilizumab (TCZ) was started with a dramatic resolution of the proteinuria, stabilization of the amyloid deposits and improvement in general condition.