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3.
Indian Dermatol Online J ; 5(4): 552-3, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25396167
4.
Indian J Dermatol ; 59(4): 423, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25071288

RESUMO

We present a case of hemorrhagic bullous dermatosis occurring in areas distant from the site of injection of enoxaparin. A 88 year old woman was admitted for inter trochantric fracture. She was put enoxaparin 60mg subcutaneous 12 hrly for deep vein thrombosis. After 5 days she developed huge hemorrhagic bulla on left leg and multiple hemorrhagic bullae at other sites distant from injected site. A diagnosis of Bullous hemorrhagic dermatoses due to enoxaparin was made. Enoxaparin was stopped and started on oral heparin. Lesions started to regress. Only 9 similar cases have been reported throughout world and none from India.

6.
Indian Dermatol Online J ; 5(2): 182-4, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24860758

RESUMO

Type 2 lepra reaction or erythema nodosum leprosum (ENL) is an immune complex syndrome that occurs mostly in lepromatous leprosy and sometimes in borderline lepromatous leprosy patients. We present an untreated case of lepromatous leprosy, who presented with type 2 lepra reaction and livedo reticularis. Livedo reticularis, though seen in lucio phenomenon, is not a part of type 2 lepra reaction. The case is being reported for its rarity.

9.
Indian Dermatol Online J ; 5(Suppl 2): S132-3, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25593806
11.
Indian J Pharmacol ; 45(1): 80-2, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23543919

RESUMO

OBJECTIVE: Cutaneous drug reactions are the most common type of adverse drug reactions. Adverse cutaneous drug reactions form 2-3% of the hospitalized patients. 2% of these are potentially serious. This study aims to detect the drugs commonly implicated in Steven Johnson Syndrome-Toxic Epidermal Necrosis (SJS-TEN). MATERIALS AND METHODS: A retrospective analysis was done in all patients admitted in the last five years in SDM hospital with the diagnosis of SJS-TEN. RESULTS: A total of 22 patients with SJS-TEN were studied. In 11 patients anti-epileptics was the causal drug and in 7, anti-microbials was the causal drug. Recovery was much faster in case of anti epileptics induced SJS-TEN as compared to that induced by ofloxacin. CONCLUSION: SJS-TEN induced by ofloxacin has a higher morbidity and mortality compared to anti convulsants.


Assuntos
Antibacterianos/efeitos adversos , Anticonvulsivantes/efeitos adversos , Ofloxacino/efeitos adversos , Síndrome de Stevens-Johnson/induzido quimicamente , Síndrome de Stevens-Johnson/etiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Índia , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
12.
Int J Trichology ; 5(3): 132-6, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24574691

RESUMO

BACKGROUND: Dermatoscopy is a new noninvasive tool for the diagnosis of various skin and hair disorders. Dermatoscopy of alopecia areata (AA) shows various specific features, which may aid in confirming the diagnosis. AIMS: The aim of this study was to determine the various clinical patterns and the dermatoscopic features of AA. MATERIALS AND METHODS: A total of 75 patients of AA were evaluated with a dermatoscope (magnification ×25 and ×60). RESULTS: The mean age of onset of AA was 23.58 years. Males were more commonly affected. Scalp was most commonly involved. Patchy alopecia was the most common pattern observed. 10 patients showed concomitant nail changes. The dermatoscopic features included yellow dots (YDs) in 43 (57.33%) patients, black dots (BDs) in 63 (84%) cases, broken hairs (BHs) in 28 (37.33%) cases, short vellus hair (SVH) in 51 (68%) patients and tapering hair (TH) in 14 (18.67%) cases. CONCLUSION: The most common dermatoscopic finding observed was BDs, followed by SVHs, YDs, BH and TH.

13.
Indian J Pharmacol ; 44(6): 798-800, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23248415

RESUMO

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and life-threatening delayed drug hypersensitivity reaction characterized by skin eruption, fever, lymphadenopathies, and visceral involvement. Here, we are presenting a 12 year old boy, who developed rare but life threatening DRESS syndrome due to Lamotrigine. Early detection and treatment led to his rapid recovery. This case is presented to highlight the importance of early detection of rare fatal syndrome.


Assuntos
Anticonvulsivantes/efeitos adversos , Hipersensibilidade a Drogas/etiologia , Eosinofilia/induzido quimicamente , Hipersensibilidade Tardia/induzido quimicamente , Triazinas/efeitos adversos , Criança , Humanos , Lamotrigina , Masculino , Síndrome
14.
Transfus Apher Sci ; 47(1): 17-9, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22475546

RESUMO

Graft-versus-host disease (GVHD) is a rare, almost always fatal complication of a blood transfusion. It occurs much more commonly after bone marrow transplantation, a setting in which it is less severe-mortality rate of 20-25% following transplantation versus 80-90% when associated with a transfusion. Transfusion associated GVHD occurs in two settings: when the recipient is immunodeficient; and when there is a specific type of partial HLA matching between the donor and recipient. Here we present a case of transfusion associated GVHD which developed when a 2 year old immunocompetent girl was given whole blood which was taken by his father. Inspite of very intense therapy with parental steroids and oral cyclosporine the child succumbed to death.


Assuntos
Anemia/terapia , Doença Enxerto-Hospedeiro/etiologia , Reação Transfusional , Pré-Escolar , Ciclosporina/administração & dosagem , Evolução Fatal , Pai , Feminino , Doença Enxerto-Hospedeiro/tratamento farmacológico , Humanos , Imunossupressores/administração & dosagem , Masculino , Esteroides/administração & dosagem
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