Concordancia diagnóstica entre atención primaria y psiquiatra en derivaciones a Centro Comunitario de Salud Mental en Talca / Diagnostic Concordance between Primary Care and psychiatrist in Communitary Mental Health Center in Talca

Psychiatric diseases have a high presence in Chilean population. Most of the cases are treated in the primary care. Despite this, and because of their complexity, some cases need specialist care. Is important the appropriate referral to secondary care which can be measured by the diagnostic concordance. The purpose of this study is to analyze the diagnostic concordance between primary care and the evaluation of Psychiatrists in secondary level at Communitary Mental Health Center (COSAM) in Talca. METHODOLOGY: Cross-sectional descriptive study. All medical files of the patients older than 15 years old treated at COSAM were examined from August 2012 to November 2013. Moreover, the diagnostics of both primary care derivation and Psychiatrists of COSAM were compared with Kappa Index. RESULTS: The general concordance between the diagnostics of primary care level and COSAM was moderated (kappa index: 0.54). Higher in men than in women. The results showed a high concordance in the diagnostic of eating disorders and Dementia, a moderated concordance in the diagnostic of Bipolar Disorder and Panic Disorder. Finally, a low concordance in the diagnostic of General Anxiety Disorder (GAD), Personality Disorder and Major Depressive Disorder.Although the concordance in the derivations to COSAM is moderated, higher than international studies, the concern is in the failure in the diagnostic of the Bipolar Disorder, an inappropriate treatment can be prescribed if there is not a correct diagnostic.

Conducta suicida en niños y adolescentes ingresados en un hospital general: Análisis descriptivo / Features of adolescents hospitalized for a suicide attempt in a general hospital

Background: Worldwide, suicide is the third cause of death among adolescents. Aim: To determine the socio-demographic context and clinical characteristics of children and adolescents hospitalized for suicidal behavior in a general hospital. Material and Methods: Between 2007 and 2009, we evaluated 47 patients with a mean age of 15.3 years (87% women) admitted for suicidal behavior at the Clinical Hospital of the Catholic University of Chile. Demographic data of the participants were registered. Clinical interviews were done by a child and adolescent psychiatrist. Results: Fifty seven percent of patients lived with both parents. Fifty one percent had previous suicide attempts and 68% had a previous psychiatric treatment. The main trigger was a conflict with parents in 66%. The psychiatric diagnoses were major depressive episode in 74.5% and pathological development of personality in 43%. All suicide attempts were with drugs and 6.4% were associated with cuts. Seventeen percent of attempts were classified as medically serious and they were more common in older age groups. Non severe attempts were observed mainly in women (92.3%). Acetaminophen intake was recorded in 8.5% of cases. Admission to hospital increased in the final quarter of the year. High costs of hospitalization were observed associated to stays in high complexity units. Conclusions: The population studied shows a high incidence of prior suicidal behavior. Most of the studied patients had attempts that were not classified as serious. These occurred predominantly in women in all age ranges. Medically serious suicidal behavior is mainly observed in older adolescents.

[Features of adolescents hospitalized for a suicide attempt in a general hospital]. / Conducta suicida en niños y adolescentes ingresados en un hospital general. Análisis descriptivo.

BACKGROUND: Worldwide, suicide is the third cause of death among adolescents. AIM: To determine the socio-demographic context and clinical characteristics of children and adolescents hospitalized for suicidal behavior in a general hospital. MATERIAL AND METHODS: Between 2007 and 2009, we evaluated 47 patients with a mean age of 15.3 years (87% women) admitted for suicidal behavior at the Clinical Hospital of the Catholic University of Chile. Demographic data of the participants were registered. Clinical interviews were done by a child and adolescent psychiatrist. RESULTS: Fifty seven percent of patients lived with both parents. Fifty one percent had previous suicide attempts and 68% had a previous psychiatric treatment. The main trigger was a conflict with parents in 66%. The psychiatric diagnoses were major depressive episode in 74.5% and pathological development of personality in 43%. All suicide attempts were with drugs and 6.4% were associated with cuts. Seventeen percent of attempts were classified as medically serious and they were more common in older age groups. Non severe attempts were observed mainly in women (92.3%). Acetaminophen intake was recorded in 8.5% of cases. Admission to hospital increased in the final quarter of the year. High costs of hospitalization were observed associated to stays in high complexity units. CONCLUSIONS: The population studied shows a high incidence of prior suicidal behavior. Most of the studied patients had attempts that were not classified as serious. These occurred predominantly in women in all age ranges. Medically serious suicidal behavior is mainly observed in older adolescents.

Evaluación de un test comercial de avidez de IgG: Aporte al diagnóstico de primoinfección por Toxoplasma gondii / Evaluation of an IgG avidity commercial test: Contribution to diagnosis of primary infection caused by Toxoplasma gondii

Introduction: Toxoplasmosis (T) is a major chronic parasitic infection in immunocompromised patients and pregnant women. It is important to discriminate between acute phase (AT) and chronic phase (CT). Diagnosis is serological in immunocompetent patients (concentration of IgG and IgM). Objective: To evaluate the utility of an IgG avidity test (A-IgG) to identify the acute and chronic stage. Avidity is the strength of affinity between a specific immunoglobulin and the protein antigenic epitope of the infecting agent, an affinity that increases over time. Patients and Methods: We used a qualitative kit that measures the avidity of IgG, discriminating the two phases. In 35 patients with clinical diagnosis of AT and/or CT, IgG, IgM and IgG A (VIDAS®) were performed. Results: Patients with AT were positive for IgM and IgG, but presented weak avidity. In the 21 cases with CT, 52 percent (n: 11) were IgM positive and 100 percent (n: 21) had positive IgG with strong avidity. Discussion: The results confirm that the test of A-IgG may be useful in the diagnosis of AT, and has 100 percent concordance with reference test (qualitative IgM + quantitative IgG). The result is available within 24 hrs, and may be useful in diagnosis of AT in pregnant women.

Introducción: Toxoplasmosis (T) es una infección parasitaria crónica importante en pacientes inmunocompro-metidos y mujeres embarazadas. Es relevante discriminar entre fase aguda (TA) y fase crónica (TC). Su diagnóstico es serológico en inmunocompetentes (detección de IgG e IgM). Objetivo: Evaluar la utilidad del test de avidez IgG (A-IgG) para identificar la fase aguda y o crónica. Avidez es la fuerza de afinidad entre una inmunoglobulina específica y el epítope de la proteína antigénica del agente infectante, afinidad que aumenta con el tiempo. Pacientes y Métodos: Se usó un test cualitativo que mide la avidez de IgG, discriminando las dos fases. A 35 pacientes con diagnóstico clínico de TA y o TC, se les realizó IgG, IgM e A-IgG en Equipo VIDAS®. Resultados: Los pacientes con TA fueron positivos para IgM e IgG y presentaron avidez débil. Los 21 casos con TC 52 por ciento (n: 11) tuvieron IgM positivo y 100 por ciento (n: 21) tuvo IgG positiva con avidez fuerte. Discusión: Los resultados confirman que el test de A-IgG puede ser de gran utilidad en el diagnóstico de TA, concordancia: 100 por ciento con test de referencia (IgM cualitativa + IgG cuantitativa). El resultado está disponible en menos de 24 hrs, pudiendo ser útil en el diagnóstico de TA en mujeres embarazadas.

[Evaluation of an IgG avidity commercial test: contribution to diagnosis of primary infection caused by Toxoplasma gondii]. / Evaluación de un test comercial de avidez de IgG: Aporte al diagnóstico de primoinfección por Toxoplasma gondii.

INTRODUCTION: Toxoplasmosis (T) is a major chronic parasitic infection in immunocompromised patients and pregnant women. It is important to discriminate between acute phase (AT) and chronic phase (CT). Diagnosis is serological in immunocompetent patients (concentration of IgG and IgM). OBJECTIVE: To evaluate the utility of an IgG avidity test (A-IgG) to identify the acute and chronic stage. Avidity is the strength of affinity between a specific immunoglobulin and the protein antigenic epitope of the infecting agent, an affinity that increases over time. PATIENTS AND METHODS: We used a qualitative kit that measures the avidity of IgG, discriminating the two phases. In 35 patients with clinical diagnosis of AT and/or CT, IgG, IgM and IgG A (VIDAS®) were performed. RESULTS: Patients with AT were positive for IgM and IgG, but presented weak avidity. In the 21 cases with CT, 52% (n: 11) were IgM positive and 100% (n: 21) had positive IgG with strong avidity. DISCUSSION: The results confirm that the test of A-IgG may be useful in the diagnosis of AT, and has 100% concordance with reference test (qualitative IgM + quantitative IgG). The result is available within 24 hrs, and may be useful in diagnosis of AT in pregnant women.