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1.
Prenat Diagn ; 31(10): 985-9, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21812008

RESUMO

OBJECTIVE: To compare the uptake of Down syndrome screening by women following referral by direct access and general practitioner (GP) modes. METHODS: The method of referral by either GP or direct access, for women who booked into prenatal care in Hull and East Yorkshire in 2010, was analysed using data collected from the Protos database at the Women and Children's Hospital, Hull. Subsequently, the uptake of first and second trimester screening for Down syndrome was reviewed by combining the Protos database to the screening data collected by the Clinical Biochemistry Laboratory at Hull Royal Infirmary, Hull. RESULTS: Women booked into prenatal care significantly earlier when referred by GP in comparison to direct access with a significant difference in screening uptake of 49.5 and 42.7%, respectively. The ratio of uptake between first and second trimester screening was not significantly different. CONCLUSIONS: Further research on the new direct access method of referral is required, as it may have a role in the uptake of prenatal screening for Down syndrome. More time is needed to show a definitive effect.


Assuntos
Síndrome de Down/diagnóstico , Programas de Rastreamento/estatística & dados numéricos , Enfermeiros Obstétricos , Cuidado Pré-Natal/métodos , Adulto , Biomarcadores/sangue , Gonadotropina Coriônica Humana Subunidade beta/sangue , Síndrome de Down/sangue , Feminino , Clínicos Gerais , Humanos , Programas de Rastreamento/métodos , Auditoria Médica , Medição da Translucência Nucal , Gravidez , Primeiro Trimestre da Gravidez/sangue , Segundo Trimestre da Gravidez/sangue , Encaminhamento e Consulta , Estudos Retrospectivos , alfa-Fetoproteínas/metabolismo
2.
Eur J Obstet Gynecol Reprod Biol ; 159(1): 95-8, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21839574

RESUMO

OBJECTIVE: To describe any trends in the uptake of antenatal screening for Down's syndrome since the addition of the earlier first trimester combined test. STUDY DESIGN: All antenatal screening tests for Down's syndrome were carried out and their results were recorded by the Clinical Biochemistry Department at the Hull Royal Infirmary (HRI) and reviewed against the antenatal booking data held at the Women and Children's Hospital at HRI. The uptake of antenatal Down's syndrome screening for 5 different age groups of women across a four-year-period from 2007 to 2010 was analysed. RESULTS: There was a significant increase in uptake of antenatal screening for Down's syndrome from 43.9% to 56.5% after the introduction of the combined test in 2010. This increase was apparent in all age groups. There was no change in the proportion of women opting for an invasive test following a positive screening test. CONCLUSION: Addition of the earlier first trimester combined test has increased uptake of antenatal screening for Down's syndrome in women of all ages. This is most likely due to the advantages this test gives women such as earlier decision making, earlier further invasive diagnostic testing and earlier termination, if necessary.


Assuntos
Síndrome de Down/diagnóstico , Aceitação pelo Paciente de Cuidados de Saúde , Diagnóstico Pré-Natal/métodos , Adolescente , Adulto , Fatores Etários , Biomarcadores/sangue , Gonadotropina Coriônica Humana Subunidade beta/sangue , Bases de Dados Factuais , Síndrome de Down/diagnóstico por imagem , Síndrome de Down/embriologia , Feminino , Humanos , Pessoa de Meia-Idade , Medição da Translucência Nucal , Gravidez , Primeiro Trimestre da Gravidez/sangue , Proteína Plasmática A Associada à Gravidez/análise , Diagnóstico Pré-Natal/psicologia , Reino Unido , Adulto Jovem
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