[Mechanism of the antiexudative action of heparin]. / K mekhanizmu antiékssudativnogo deistviia geparina.

The skin inflammation was induced by xylol application in experiments on rats. Exogenous and endogenous hyperheparinemia was found not to influence the dynamics of microcirculatory changes in the inflammatory area at the onset of its development, vascular permeability being significantly decreased. It is suggested that decreased vascular permeability plays an important role in the mechanism of antiexudative heparin action.

[Concentration of components of the adenylate system in the liver during cholestasis]. / Soderzhanie komponentov adenilovoi sistemy v pecheni pri kholestaze

Content of adenyl system components, inorganic phosphate as well as the glucose-6-phosphate dehydrogenase activity were studied in rat liver tissue under extrahepatic cholestasis. Cholestasis was caused by ligation of the general biliary duct. The correlation was observed between the increase in total bilirubin in blood plasma and the decrease in content of inorganic phosphate. The glucose-6-phosphate dehydrogenase activity was unaltered.