Multireflection propagation of conformational kinks in a two-component model of DNA as the transfer mode of the transcriptional replication fork.

The propagation, or movement, of a conformational kink along a linear structure can occur in capture, transfer, or multireflection modes. Here we use a model for two-component bistable polymer molecules with energetically non-equivalent stable states to model the propagation of the DNA transcription bubble via movement of a non-linear longitudinal stretching region along the DNA chain. We show that under certain conditions the longitudinal excitation can act as a reflector for a conformational kink and, furthermore, that conformational switching may propagate in a multireflection mode alongside conformational kink transition and conformational kink trapping.

Non-linear longitudinal compression effect on dynamics of the transcription bubble in DNA.

The dependence of the dynamics of transcription bubble on the parameters of non-linear longitudinal compression is presented on the base of simple model of soliton-like conformational switchings in two-component bistable polymer molecules with energetically non-equivalent stable states. It has been shown that under certain conditions the longitudinal compression may be a trap for a conformational switching.

Multicore fiber with rectangular cross-section.

We have fabricated, to our knowledge, the first rectangular cross-section multicore fiber with eight cores arranged in a line. We have shown that the rectangular cross-section remains practically unchanged during the fiber-drawing process. The heterogeneous version of the proposed fiber design could be beneficial for crosstalk reduction because of the low influence of fiber bends on crosstalk between neighboring cores.

[The relationship of the treatment results in acute pancreatitis to the correctness of the diagnosis of the stages of the disease]. / Zavisimost' rezul'tatov lecheniia ostrogo pankreatita ot pravil'nosti diagnostiki stadii zabolevaniia.

An analysis of 77 case histories of people who died from destructive pancreatitis is presented. Medico-tactical errors and complications were found out. A differentiated approach to treatment of acute pancreatitis was shown to be necessary depending on the stage of the disease. Preference is given to complex conservative therapy with the closed-type little-invasive operations. The total amount of patients with acute pancreatitis for the period under analysis is 1644. Postoperative lethality was 46%, total lethality--4.7%.