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J Therm Biol ; 100: 103073, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34503810

RESUMO

Hyperthermia technique has received much attention over the last decade being less invasive among the others. Laser therapy is among the most commonly investigated types of ablative hyperthermia for treatment of cancer. In this method an external heat source provided by a laser fiber leads the cancerous tissue to the necrosis stage. For its simulation a cylindrical geometry of a breast tissue containing a tumor is acted upon by a Gaussian form of laser radiation. Then the feasibility of a fat layer injection around the tumor during the therapy is investigated numerically. In order to consider the finite speed of heat transfer, dual phase lag (DPL) model is implemented for prediction of the thermal results. The therapy is addressed with and without the presence of a fat layer around the breast tumor. Results show that the temperature in the tumor increases up to 15 % by the injection of a fat layer. Also, the presence of a fat layer around the tumor shows that the irreversible ablation happens at a faster rate.


Assuntos
Neoplasias da Mama/terapia , Convecção , Terapia a Laser/métodos , Modelos Teóricos , Tecido Adiposo/efeitos da radiação , Feminino , Análise de Elementos Finitos , Humanos , Glândulas Mamárias Humanas/efeitos da radiação
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