RESUMO
Spatial EEG factor analysis was performed in patients under gamonil and damilen treatment. Groups of EEG-factors were discovered that describe the peculiarities of the brain electrical processes spatial reorganization under pharmacotherapy. Major groups comprised the EEG factors: 1. characterizing the proper action of the drug; 2. connected to the syndromal peculiarities of depression or the course of mental state changes; 3. those depending on the efficiency of the therapy.
Assuntos
Amitriptilina/análogos & derivados , Amitriptilina/uso terapêutico , Antidepressivos/uso terapêutico , Córtex Cerebral/efeitos dos fármacos , Transtorno Depressivo/tratamento farmacológico , Dibenzazepinas/uso terapêutico , Lofepramina/uso terapêutico , Esquizofrenia/complicações , Potenciais de Ação/efeitos dos fármacos , Potenciais de Ação/fisiologia , Adulto , Córtex Cerebral/fisiopatologia , Transtorno Depressivo/etiologia , Transtorno Depressivo/fisiopatologia , Eletroencefalografia , Análise Fatorial , Feminino , Humanos , Pessoa de Meia-Idade , Esquizofrenia/fisiopatologiaRESUMO
Methods of factorial and discriminant analysis were used for the analysis of the electroencephalographic reaction to gamonil and damilen. Specific features of EEG spatial reorganization were revealed for each of the thymoleptics which made it possible to recognize correctly the drugs in 87.5 and 92.3% of cases, respectively.
