RESUMO
The literature on HIV therapeutics research is rife with terminology associating 'sterilisation' with HIV cure. We find connotations of the word 'sterilising' problematic for the HIV cure research field. In this viewpoint, we review associations of sterilising with concepts of disinfection or cleansing, as well as coerced sterilisation. We discuss emerging findings from socio-behavioural research that show aversion from people living with HIV towards the 'sterilising cure' nomenclature. We call for more collaborations with people with HIV as partners to help define what would be a more acceptable terminology for describing an HIV cure.
Assuntos
Infecções por HIV/história , Sobreviventes de Longo Prazo ao HIV/psicologia , Saúde Holística/história , Saúde Mental , Leucemia-Linfoma Linfoblástico de Células Precursoras/história , Adaptação Psicológica , Criança , Terapia Combinada , Infecções por HIV/mortalidade , Infecções por HIV/psicologia , Infecções por HIV/terapia , História do Século XX , Humanos , Leucemia-Linfoma Linfoblástico de Células Precursoras/mortalidade , Leucemia-Linfoma Linfoblástico de Células Precursoras/psicologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Meio Social , Estados UnidosAssuntos
Atenção à Saúde/organização & administração , Infecções por HIV/tratamento farmacológico , Infecções por HIV/psicologia , Comportamento Sexual/fisiologia , Sífilis/tratamento farmacológico , Sífilis/psicologia , Venereologia/organização & administração , Atenção à Saúde/métodos , Atenção à Saúde/tendências , Infecções por HIV/epidemiologia , Infecções por HIV/transmissão , Humanos , Especialização , Sífilis/epidemiologia , Sífilis/transmissão , Venereologia/métodos , Venereologia/tendênciasRESUMO
Hereditary non-polyposis colorectal cancer (HNPCC) helps us understand how medical genetics has changed over the last forty years. The concept of the "cancer family" emerged from the realization that members of some families developed cancer more frequently than members of others, which led to a series of strategies by clinicians in the 1960s to persuade others of this. By the early 1990s molecular genetics had transformed the disease, from one that a few physicians believed ran in families, to one with precise genetic components that researchers generally accepted, and that could be detected through genetic tests. Nevertheless, a diagnosis of HNPCC still requires that the mutated genes be found within a kin group that is generally accepted as a cancer family. Moreover, the "cancer family" construct was crucial in the search for the HNPCC genes. HNPCC's trajectory can be mapped onto important debates about the complex relations between clinical and molecular genetics knowledge and practice.
