1.
Org Lett
; 2(23): 3687-9, 2000 Nov 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11073676
RESUMO
A strictly "pair"-selective synthesis of conjugated diynes via Pd-catalyzed cross coupling of 1,3-diynylzincs is described. This method, like the Cadiot-Chodkiewicz reaction, requires three steps for the synthesis of R(1)Ctbd1;CCtbd1;CR(2) from R(1)Ctbd1;CH, R(2)X, and HCtbd1;CH. However, the high "pair"-selectivity permitting high-yield production of the desired conjugated diynes without separation of symmetrical diynes promises to make the present protocol superior to the Cadiot-Chodkiewicz reaction in many cases.
Assuntos
Alcinos/síntese química , Compostos Organometálicos/síntese química , Zinco , Alcinos/química , Catálise , Indicadores e Reagentes , Compostos Organometálicos/química , Paládio
2.
J Am Chem Soc
; 95(20): 6837-8, 1973 Oct 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4746280