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1.
Front Comput Neurosci ; 12: 103, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30622466

RESUMO

Hough transform (HT) is one of the most well-known techniques in computer vision that has been the basis of many practical image processing algorithms. HT however is designed to work for frame-based systems such as conventional digital cameras. Recently, event-based systems such as Dynamic Vision Sensor (DVS) cameras, has become popular among researchers. Event-based cameras have a significantly high temporal resolution (1 µs), but each pixel can only detect change and not color. As such, the conventional image processing algorithms cannot be readily applied to event-based output streams. Therefore, it is necessary to adapt the conventional image processing algorithms for event-based cameras. This paper provides a systematic explanation, starting from extending conventional HT to 3D HT, adaptation to event-based systems, and the implementation of the 3D HT using Spiking Neural Networks (SNNs). Using SNN enables the proposed solution to be easily realized on hardware using FPGA, without requiring CPU or additional memory. In addition, we also discuss techniques for optimal SNN-based implementation using efficient number of neurons for the required accuracy and resolution along each dimension, without increasing the overall computational complexity. We hope that this will help to reduce the gap between event-based and frame-based systems.

2.
Lasers Med Sci ; 31(2): 305-14, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26719056

RESUMO

Osteoporosis (OP) increases vertebral fragility as a result of the biomechanical effects of diminished bone structure and composition. This study has aimed to assess the effects of pulsed wave low-level laser therapy (PW LLLT) on cancellous bone strength of an ovariectomized (OVX-d) experimental rat model and a glucocorticoid-induced OP (GIOP) experimental rat model. There were four OVX-d groups and four dexamethasone-treated groups. A group of healthy rats was used for baseline evaluations. The OVX-d rats were further subdivided into the following groups: control rats with OP, OVX-d rats that received alendronate, OVX-d rats treated with PW LLLT, and OVX-d rats treated with alendronate and PW LLLT. The remaining rats received dexamethasone and were divided into four groups: control, alendronate-treated rats, laser-treated rats, and laser-treated rats with concomitant administration of alendronate. PW LLLT (890 nm, 80 Hz, 0.972 J/cm(2)) was performed on the spinal processes of the T12, L1, L2, and L3 vertebras. We extracted the L1 vertebrae and submitted them to a mechanical compression test. Biomechanical test findings showed positive effects of the PW LLLT and alendronate administration on increasing bending stiffness and maximum force of the osteoporotic bones compared to the healthy group. However, laser treatment of OVA-d rats significantly increased stress high load compared to OVA-d control rats. PW LLLT preserved the cancellous (trabecular) bone of vertebra against the detrimental effects of OV-induced OP on bone strength in rats compared to control OV rats.


Assuntos
Terapia com Luz de Baixa Intensidade , Fenômenos Mecânicos , Osteoporose/fisiopatologia , Osteoporose/radioterapia , Coluna Vertebral/fisiopatologia , Coluna Vertebral/efeitos da radiação , Alendronato/uso terapêutico , Animais , Fenômenos Biomecânicos/efeitos dos fármacos , Fenômenos Biomecânicos/efeitos da radiação , Feminino , Glucocorticoides/efeitos adversos , Masculino , Osteoporose/induzido quimicamente , Osteoporose/tratamento farmacológico , Ovariectomia , Ratos , Ratos Sprague-Dawley , Coluna Vertebral/efeitos dos fármacos
3.
Biol Psychol ; 115: 35-42, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26777128

RESUMO

An evolutionarily ancient skill we possess is the ability to distinguish between food and non-food. Our goal here is to identify the neural correlates of visually driven 'edible-inedible' perceptual distinction. We also investigate correlates of the finer-grained likability assessment. Our stimuli depicted food or non-food items with sub-classes of appealing or unappealing exemplars. Using data-classification techniques drawn from machine-learning, as well as evoked-response analyses, we sought to determine whether these four classes of stimuli could be distinguished based on the patterns of brain activity they elicited. Subjects viewed 200 images while in a MEG scanner. Our analyses yielded two successes and a surprising failure. The food/non-food distinction had a robust neural counterpart and emerged as early as 85 ms post-stimulus onset. The likable/non-likable distinction too was evident in the neural signals when food and non-food stimuli were grouped together, or when only the non-food stimuli were included in the analyses. However, we were unable to identify any neural correlates of this distinction when limiting the analyses only to food stimuli. Taken together, these positive and negative results further our understanding of the substrates of a set of ecologically important judgments and have clinical implications for conditions like eating-disorders and anhedonia.


Assuntos
Discriminação Psicológica/fisiologia , Alimentos , Reconhecimento Visual de Modelos/fisiologia , Adolescente , Adulto , Nível de Alerta/fisiologia , Córtex Cerebral/fisiologia , Transtornos da Alimentação e da Ingestão de Alimentos/fisiopatologia , Feminino , Preferências Alimentares/fisiologia , Humanos , Aprendizado de Máquina , Magnetoencefalografia , Masculino , Estatística como Assunto , Adulto Jovem
4.
Iran Red Crescent Med J ; 17(3): e19389, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26019900

RESUMO

BACKGROUND: Osteoporosis is a disease, which causes bone loss and fractures. Although glucocorticoids effectively suppress inflammation, their chronic use is accompanied by bone loss with a tendency toward secondary osteoporosis. OBJECTIVES: This study took into consideration the importance of cortical bone in the entire bone's mechanical competence. Hence, the aim of this study was to assess the effects of different protocols of glucocorticoid administration on the biomechanical properties of tibial bone diaphysis in rats compared to control and low-level laser-treated rats. MATERIALS AND METHODS: This experimental study was conducted at Shahid Beheshti University of Medical Sciences, Tehran, Iran. We used systematic random sampling to divide 40 adult male rats into 8 groups with 5 rats in each group. Groups were as follows: 1) control, 2) dexamethasone (7 mg/week), 3) dexamethasone (0.7 mg/week), 4) methylprednisolone (7 mg/kg/week), 5) methylprednisolone (5 mg/kg twice weekly), 6) dexamethasone (7 mg/kg three times per week), 7) dexamethasone (0.7 mg/kg thrice per week), and 8) low-level laser-treated rats. The study periods were 4-7 weeks. At the end of the treatment periods, we examined the mechanical properties of tibial bone diaphysis. Data were analyzed by statistical analyses. RESULTS: Glucocorticoid-treated rats showed weight loss and considerable mortality (21%). The biomechanical properties (maximum force) of glucocorticoid-treated rats in groups 4 (62 ± 2.9), 6 (63 ± 5.1), and 7 (60 ± 5.3) were comparable with the control (46 ± 1.5) and low-level laser-treated (57 ± 3.2) rats. CONCLUSIONS: In contrast to the findings in humans and certain other species, glucocorticoid administration caused anabolic effect on the cortical bone of tibia diaphysis bone in rats.

5.
Lasers Med Sci ; 30(3): 1117-25, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25616711

RESUMO

Osteoporosis (OP) is a disease which causes bone loss and fractures, leading to severe pain and deformity. This study has aimed to assess the effects of pulsed wave low-level laser therapy (PW LLLT) on cortical bone in two experimental models of OP in rats. There were four ovariectomized (OVX-d) groups and four dexamethasone-treated groups. The healthy group were considered for baseline evaluations. At 14 weeks following ovariectomy, the OVX-d rats were further subdivided into the following: control rats with OP, OVX-d rats that received alendronate (1 mg/kg), OVX-d rats treated with LLLT, and OVX-d rats treated with alendronate and LLLT. The remaining rats received dexamethasone for 5 weeks and were divided into four groups: control, alendronate-treated rats (1 mg/kg), laser-treated rats, and laser-treated rats with concomitant administration of alendronate. The rats received alendronate for 30 days. LLLT (890 nm, 80 Hz, 0.972 J/cm(2)) was performed on the tibias three times per week for 8 weeks. After 8 weeks, tibias were extracted and submitted to a three-point bending test. PW LLLT did not increase the biomechanical parameters of osteoporotic bones compared to controls and healthy rats. PW LLLT associated with alendronate treatment significantly increased stress high load in OVX-d rats compared to the healthy group. PW LLLT at the current study parameters failed to cause beneficial biomechanical effects in the examined osteoporotic cortical bones. PW LLLT associated with alendronate treatment produced a more remarkable effect on bone strength in the ovariectomized induced OP rat model.


Assuntos
Terapia com Luz de Baixa Intensidade , Osteoporose/radioterapia , Alendronato/uso terapêutico , Animais , Fenômenos Biomecânicos , Conservadores da Densidade Óssea/uso terapêutico , Quimiorradioterapia , Diáfises/efeitos da radiação , Feminino , Humanos , Masculino , Ratos , Ratos Wistar , Tíbia/fisiopatologia , Tíbia/efeitos da radiação
6.
Annu Int Conf IEEE Eng Med Biol Soc ; 2015: 1480-3, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26736550

RESUMO

Brain computer interface (BCI) technology is becoming increasingly popular in many domains such as entertainment, mental state analysis, and rehabilitation. For robust performance in these domains, detecting perceptual events would be a vital ability, enabling adaptation to and act on the basis of user's perception of the environment. Here we present a framework to automatically mine spatiotemporal characteristics of a given perceptual event. As this "signature" is derived directly from subject's neural behavior, it can serve as a representation of the subject's perception of the targeted scenario, which in turn allows a BCI system to gain a new level of context awareness: perception awareness. As a proof of concept, we show the application of the proposed framework on MEG signal recordings from a face perception study, and the resulting temporal and spatial characteristics of the derived neural signature, as well as it's compatibility with the neuroscientific literature on face perception.


Assuntos
Conscientização , Adaptação Fisiológica , Encéfalo , Interfaces Cérebro-Computador , Eletroencefalografia , Humanos , Percepção
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