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1.
Comput Biol Med ; 155: 106613, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36764157

RESUMO

Explainable Artificial Intelligence (XAI) makes AI understandable to the human user particularly when the model is complex and opaque. Local Interpretable Model-agnostic Explanations (LIME) has an image explainer package that is used to explain deep learning models. The image explainer of LIME needs some parameters to be manually tuned by the expert in advance, including the number of top features to be seen and the number of superpixels in the segmented input image. This parameter tuning is a time-consuming task. Hence, with the aim of developing an image explainer that automizes image segmentation, this paper proposes Ensemble-based Genetic Algorithm Explainer (EGAE) for melanoma cancer detection that automatically detects and presents the informative sections of the image to the user. EGAE has three phases. First, the sparsity of chromosomes in GAs is determined heuristically. Then, multiple GAs are executed consecutively. However, the difference between these GAs are in different number of superpixels in the input image that result in different chromosome lengths. Finally, the results of GAs are ensembled using consensus and majority votings. This paper also introduces how Euclidean distance can be used to calculate the distance between the actual explanation (delineated by experts) and the calculated explanation (computed by the explainer) for accuracy measurement. Experimental results on a melanoma dataset show that EGAE automatically detects informative lesions, and it also improves the accuracy of explanation in comparison with LIME efficiently. The python codes for EGAE, the ground truths delineated by clinicians, and the melanoma detection dataset are available at https://github.com/KhaosResearch/EGAE.


Assuntos
Inteligência Artificial , Melanoma , Humanos , Óxidos
2.
J Supercomput ; 78(18): 19725-19753, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35789817

RESUMO

One of the major problems in microarray datasets is the large number of features, which causes the issue of "the curse of dimensionality" when machine learning is applied to these datasets. Feature selection refers to the process of finding optimal feature set by removing irrelevant and redundant features. It has a significant role in pattern recognition, classification, and machine learning. In this study, a new and efficient hybrid feature selection method, called Garank&rand, is presented. The method combines a wrapper feature selection algorithm based on the genetic algorithm (GA) with a proposed filter feature selection method, SLI-γ. In Garank&rand, some initial solutions are built regarding the most relevant features based on SLI-γ, and the remaining ones are only the random features. Eleven high-dimensional and standard datasets were used for the accuracy evaluation of the proposed SLI-γ. Additionally, four high-dimensional well-known datasets of microarray experiments were used to carry out an extensive experimental study for the performance evaluation of Garank&rand. This experimental analysis showed the robustness of the method as well as its ability to obtain highly accurate solutions at the earlier stages of the GA evolutionary process. Finally, the performance of Garank&rand was also compared to the results of GA to highlight its competitiveness and its ability to successfully reduce the original feature set size and execution time.

3.
Genomics ; 112(2): 1173-1181, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31276753

RESUMO

Gene selection is the process of selecting the optimal feature subset in an arbitrary dataset. The significance of gene selection is in high dimensional datasets in which the number of samples and features are low and high respectively. The major goals of gene selection are increasing the accuracy, finding the minimal effective feature subset, and increasing the performance of evaluations. This paper proposed two heuristic methods for gene selection, namely, Xvariance against Mutual Congestion. Xvariance tries to classify labels using internal attributes of features however Mutual Congestion is frequency based. The proposed methods have been conducted on eight binary medical datasets. Results reveal that Xvariance works well with standard datasets, however Mutual Congestion improves the accuracy of high dimensional datasets considerably.


Assuntos
Bases de Dados Genéticas , Neoplasias/genética , Máquina de Vetores de Suporte , Humanos , Neoplasias/patologia
4.
Genomics ; 111(6): 1946-1955, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-30660788

RESUMO

Feature selection is the problem of finding the best subset of features which have the most impact in predicting class labels. It is noteworthy that application of feature selection is more valuable in high dimensional datasets. In this paper, a filter feature selection method has been proposed on high dimensional binary medical datasets - Colon, Central Nervous System (CNS), GLI_85, SMK_CAN_187. The proposed method incorporates three sections. First, whale algorithm has been used to discard irrelevant features. Second, the rest of features are ranked based on a frequency based heuristic approach called Mutual Congestion. Third, majority voting has been applied on best feature subsets constructed using forward feature selection with threshold τ = 10. This work provides evidence that Mutual Congestion is solely powerful to predict class labels. Furthermore, applying whale algorithm increases the overall accuracy of Mutual Congestion in most of the cases. The findings also show that the proposed method improves the prediction with selecting the less possible features in comparison with state of the arts. https://github.com/hnematzadeh.


Assuntos
Algoritmos , Bases de Dados Factuais , Baleias , Animais , Sistema Nervoso Central , Colo , Probabilidade , Máquina de Vetores de Suporte
5.
ScientificWorldJournal ; 2014: 847930, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25110748

RESUMO

Workflow-based web service compositions (WB-WSCs) is one of the main composition categories in service oriented architecture (SOA). Eflow, polymorphic process model (PPM), and business process execution language (BPEL) are the main techniques of the category of WB-WSCs. Due to maturity of web services, measuring the quality of composite web services being developed by different techniques becomes one of the most important challenges in today's web environments. Business should try to provide good quality regarding the customers' requirements to a composed web service. Thus, quality of service (QoS) which refers to nonfunctional parameters is important to be measured since the quality degree of a certain web service composition could be achieved. This paper tried to find a deterministic analytical method for dependability and performance measurement using Colored Petri net (CPN) with explicit routing constructs and application of theory of probability. A computer tool called WSET was also developed for modeling and supporting QoS measurement through simulation.


Assuntos
Internet/normas , Modelos Teóricos , Fluxo de Trabalho , Humanos
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