[Deficiency polyneuropathy secondary to immunoproliferative disease of the small intestine]. / Polineuropatía carencial secundaria a enfermedad inmunoproliferativa de intestino delgado.

We report a new case of immunoproliferative small intestinal disease with neurological involvement expressed as deficiency polyneuropathy. In spite of non identifiable plasmatic paraprotein, the use of immunohistochemical techniques showed the characteristic proliferation in the intestinal mucosa of plasma cells with a prevalence of IgA cells, which define this disease.

[Gammagraphy with labeled leukocytes as an activity and extension index of Crohn disease]. / Gammagrafía con leucocitos marcados como índice de actividad y extensión de la enfermedad de Crohn.

The knowledge of the location and extent of bowel involment and disease activity can be an important aspect on the evaluation of inflammatory bowel disease. Thirty five patients of Crohn's disease (CD) have been studied in this sense. We performed a total of 44 scintigraphic examinations using 99mTc-HMPAO labeled leukocytes and the results were compared with several clinical-biological indexes and with radiology and endoscopy. The Tc scan was the most sensitive (84.3%) and specific (100%) activity index and showed an excellent correlation with radiology and/or endoscopy in the assessment of extent of disease. Leukocyte scanning brought useful information for the management of stenosis in CD.

[The epidemiological aspects of Crohn's disease in Zaragoza]. / Aspectos epidemiológicos de la enfermedad de Crohn en Zaragoza.

Crohn's disease (CD) incidence is characterized by a wide variability in different countries. In our area it hasn't developed yet any epidemiologic study about this disease. We have reviewed fifty-four new cases diagnosed in Zaragoza University Clinical Hospital (Spain) during the period 1974-1988. The most striking facts were that the incidence of Crohn's Disease increased steadily during the 15-year period studied and the existence of a statistical association between smoking and CD. Other features were similar those previously described in the literature.