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1.
Eksp Onkol ; 8(4): 59-61, 1986.
Artigo em Russo | MEDLINE | ID: mdl-3757886

RESUMO

The paper deals with the carcinostatic and immunomodifying action of synthetic polyelectrolytes containing acid and basic groups as well as of polyampholytes and nonionogenic polymers. Polyacrylic acid was found to possess the highest antitumour and adjuvant activity. The antitumour effect of polyacrylic acid increases with its molecular mass. Introduction of other polymers into a polymer chain of acrylic acid results in a decrease in its antitumour and immunoadjuvant action.


Assuntos
Resinas Acrílicas , Adjuvantes Imunológicos , Antineoplásicos , Resinas Acrílicas/imunologia , Resinas Acrílicas/uso terapêutico , Adjuvantes Imunológicos/imunologia , Animais , Antineoplásicos/uso terapêutico , Neoplasias Hepáticas Experimentais/tratamento farmacológico , Camundongos
5.
Vopr Med Khim ; 22(6): 732-5, 1976.
Artigo em Russo | MEDLINE | ID: mdl-829192

RESUMO

Content of thiamine and activities of two enzymes were studied in blood cells of patients with various types of leukosis. In patients with acute leukemia content of thiamin was decreased in leucocytes and blood plasma. Content of vitamin B1 was increased in erythroid cells of peripheric blood in erythroleukosis. Administration of thiamin into some patients caused a distinct increase in its content in blood cells. The guanosine phosphorylase activity was higher in blood cells in leukosis as compared with control. The transketolase activity was not distinctly altered.


Assuntos
Leucemia/sangue , Pentosiltransferases/sangue , Purina-Núcleosídeo Fosforilase/sangue , Tiamina/sangue , Transcetolase/sangue , Doença Aguda , Células Sanguíneas/metabolismo , Eritrócitos/enzimologia , Nucleotídeos de Guanina , Humanos , Leucemia Eritroblástica Aguda/sangue , Leucemia Mieloide/sangue , Leucócitos/enzimologia , Tiamina Pirofosfato
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