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1.
Clin Imaging ; 69: 158-168, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32853843

RESUMO

Tuberculosis is a worldwide pandemic. Estimated that about 25% humans are colonized by Mycobacterium tuberculosis and about 1% are believed to develop the infection in the central nervous system (CNS-TB). Given the importance of this disease and its high levels of morbidity and mortality, it is imperative that every radiologist must be reminded of the most common findings of CNS-TB as there are several related differential diagnoses for this disease. The most common form CNS-TB is tuberculous meningitis (TBM), characterized mostly by basal meningitis, but infarction, hydrocephalus and tuberculomas could be present. Intracerebral tuberculosis is characterized by tuberculomas that can have different imaging features according to their stage. Vascular and spinal complications of tuberculosis are also reported. This review compiles the classic and unusual findings regarding CNS-TB together with new diagnostic scores in which neuroimaging have an important role.


Assuntos
Medula Espinal , Tuberculose Meníngea , Sistema Nervoso Central , Humanos , Imageamento por Ressonância Magnética , Medula Espinal/diagnóstico por imagem , Medula Espinal/microbiologia , Tuberculose Meníngea/diagnóstico por imagem
2.
Diagn Cytopathol ; 28(5): 274-7, 2003 May.
Artigo em Inglês | MEDLINE | ID: mdl-12722124

RESUMO

The purpose of this report is to describe the unique cytological findings of a new recently characterized type of meningioma that has extensive noncalcifying collagenous whorls and glial fibrillary acid protein (GFAP) expression. This new entity, described by Haberler and colleagues, was named whorling sclerosing variant of meningioma. The patient was a 34-yr-old white man with a large tumor in the brainstem. Intraoperative smear preparations showed a tumor with a large number of solid hyaline masses in a loose background and in focal areas tumor cells formed cohesive nests with a somewhat whorling appearance. The histological sections showed a neoplasia composed of innumerable eosinophilic, collagenous, noncalcified round deposits, cuffed by scattered meningothelial tumor cells. The neoplastic cells showed diffuse cytoplasmic reactivity for EMA and vimentin, as well as positivity to GFAP. This is the first cytological description of this new entity in the literature.


Assuntos
Citodiagnóstico , Proteína Glial Fibrilar Ácida/biossíntese , Neoplasias Meníngeas/patologia , Meningioma/patologia , Adulto , Neoplasias Encefálicas/patologia , Colágeno/ultraestrutura , Diagnóstico Diferencial , Humanos , Imuno-Histoquímica , Imageamento por Ressonância Magnética , Masculino , Neoplasias Meníngeas/metabolismo , Neoplasias Meníngeas/ultraestrutura , Meningioma/metabolismo , Meningioma/ultraestrutura
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