RESUMO
INTRODUCTION: The motility of the pharynx, upper esophageal sphincter (UES), and proximal esophagus is still poorly understood. These structures have anatomical and functional peculiarities that hinder the accurate study of their motility with the technology traditionally available. High-resolution manometry (HRM) has characteristics that make it more suitable for the study of the upper digestive tract. This study aims to evaluate in healthy volunteers, using HRM and transnasal pharyngoscopy, (1) the correlation between anatomical landmarks and HRM plots and (2) the normal values for manometric parameters of the pharynx, UES, and proximal esophagus. METHODS: We studied 40 asymptomatic volunteers with HRM (50 % male; median age, 27 years). Fourteen of those also underwent transnasal pharyngoscopy. RESULTS AND DISCUSSION: Pharyngeal peak pressure, rise time, recovery time, and duration of contraction were 128 mmHg (range, 100164 mmHg), 197 ms (range, 169268 ms), 385 ms (range, 285465 ms), and 604 ms (range, 544626 ms) at the velum and 116 mmHg (range, 97139 mmHg), 128 ms (range, 100156 ms), 194 ms (range, 148219 ms), and 336 ms (range, 267386 ms) at the epiglottis, respectively. UES extension, basal pressure, residual pressure, and duration of relaxation were 3 cm (range, 2.63.6 cm), 76 mmHg (range, 58109 mmHg), 4.4 mmHg (range, 1.26.9 mmHg), and 678 ms (range, 636757 ms), respectively. In the proximal esophagus, wave amplitudes at 2, 4, and 6 cm below the UES were 72 mmHg (range, 5397 mmHg), 56 mmHg (range, 4276 mmHg), and 48 mmHg (range, 3559 mmHg), respectively. CONCLUSIONS: In conclusion, normal values were established. These values may prove clinically useful and could contribute to future studies with dysphagic patients.