Synthesis of Hybrid Ligands with Nitrile and Cage Phosphane Donor Groups and their Applications in Gold-Mediated Reactions.

Altering the donor properties of phosphane ligands through substituent variation is an established tool in coordination chemistry and catalysis. This contribution describes the synthesis of two new hybrid donors (L) combining 1,3,5,7-tetramethyl-2,4,6-trioxa-8-phosphaadamantane-8-yl (PCg) and nitrile donor groups at different molecular scaffolds, viz. ferrocene-1,1'-diyl (fc) and 1,2-phenylene. These ligands were used to prepare dimeric Au(I) complexes [Au2 (µ(P,N)-L)2 ][SbF6 ]2 , which were evaluated as silver-free, preformed catalysts in Au-mediated cycloisomerization of (Z)-3-methylpent-2-en-4-yn-1-ol to 2,3-dimethylfuran. The catalyst featuring the ferrocene-based ligand, viz., [Au2 (µ(P,N)-CgPfcCN)2 ][SbF6 ]2 , showed the best catalytic performance at low catalyst loading (0.5 or 0.15 mol.%), which exceeded that of its diphenylphosphanyl analog [Au2 (µ(P,N)-Ph2 PfcCN)2 ][SbF6 ]2 studied earlier and the prototypical Au(I) precatalyst [Au(PPh3 )(MeCN)][SbF6 ].

Directed Design of a AuI Complex with a Reduced Mesoionic Carbene Radical Ligand: Insights from 1,2,3-Triazolylidene Selenium Adducts and Extensive Electrochemical Investigations.

Carbene-based radicals are important for both fundamental and applied chemical research. Herein, extensive electrochemical investigations of nine different 1,2,3-triazolylidene selenium adducts are reported. It is found that the half-wave potentials of the first reduction of the selones correlate with their calculated LUMO levels and the LUMO levels of the corresponding triazolylidene-based mesoionic carbenes (MICs). Furthermore, unexpected quasi-reversibility of the reduction of two triazoline selones, exhibiting comparable reduction potentials, was discovered. Through UV/Vis/NIR and EPR spectroelectrochemical investigations supported by DFT calculations, the radical anion was unambiguously assigned to be triazoline centered. This electrochemical behavior was transferred to a triazolylidene-type MIC-gold phenyl complex resulting in a MIC-radical coordinated AuI species. Apart from UV-Vis-NIR and EPR spectroelectrochemical investigations of the reduction, the reduced gold-coordinated MIC radical complex was also formed in situ in the bulk through chemical reduction. This is the first report of a monodentate triazolylidene-based MIC ligand that can be reduced to its anion radical in a metal complex. The results presented here provide design principles for stabilizing radicals based on MICs.