[The Prague Diabetes Registry. 3. Retinopathies, nephropathies and neuropathies in type 1 diabetics. The Prague Diabetes Collective]. / Prazský registr diabetiku. 3. cást. Retinopatie, nefropatie a neuropatie u diabetiku 1. typu. Kolektiv prazských diabetologu.

In the Prague register of all adult diabetics by April 1, 1992 data on 1443 patients above 18 years with type 1 DM were recorded. In 42.2% of diabetics diabetic retinopathy was observed which is manifested most frequently after 11 to 15 years' persistence of diabetes. Proteinuria, the first sign of diabetic nephropathy, was found in 13.8% of the group, 5.4% of the diabetics are in the stage of renal insufficiency. Nephropathy is 3 to 4 times more frequent in diabetics with retinopathy. Peripheral neuropathy is found in 32.8% type 1 diabetics.

[The Prague Diabetes Registry--computer utilization. 2. Body mass index, family history, manifestation of diabetes mellitus]. / Prazský registr diabetiku--vyuzití pocítace. 2. cást. Body mass index, rodinná anamnéza, zpusob manifestace diabetes mellitus.

Eighty percent of all diabetic patients in Prague, incl. those with IGT, are overweight. There are 4.6 times as many obese female diabetics, as compared with normal weight type 2 diabetics. Among type 2 male diabetics there are 1.9 times more obese ones. A familial incidence of diabetes is reported by 42% type 1 diabetics and 36% type 2 diabetics. In 64.7% of type 2 diabetics diabetes was detected accidentally. In the group of type 1 diabetics in 92.1% diabetes was detected from clinical manifestations incl. coma.

[Follow-up of newly diagnosed patients with diabetes in the Prague population. I. Incidence of diabetes and disorders of glucose tolerance, methods of detection, complications]. / Sledování nove odhalených nemocných cukrovkou v prazské populaci. I. cást: Incidence cukrovky a poruch glukózové tolerance, zpusob odhalení, komplikace.

The authors followed up the incidence of new cases of diabetes in nine Prague diabetological clinics, the way of manifestation of diabetes and its detection, age dependence, seasonal character and incidence of complications. The incidence of type 2 diabetes was 269, of type 1 2.3 and impaired glucose tolerance 27 per 100,000 population. In 76% diabetes was detected accidentally, most frequently by the health community doctor or factory medical officer; 65% of the diabetes were older than 60 years. 51% suffered from hypertension and in 0.9% of type 2 diabetics retinopathy was found.

[A genetic registry of pregnant women--SEGRAV]. / Genetický registr gravidních zen--SEGRAV.

The authors describe the structure, contents and use of a genetic register of pregnant women examined at the department of medical genetics. They discuss in detail the investigated data and their classification. The programme makes it possible to use a computer for the longitudinal follow up of the course of pregnancy and the implementation of recommended preventive measures and processing of data for medical statistics. Perspectively the register will be used for evaluation of the validity of genetic prognoses and effectiveness of preventive genetic methods. The register is used in routine practice of genetic clinics since September 1986. The authors give also an account of the experience with the genetic register.