Toxicity of synthetic musks to early life stages of the freshwater mussel Lampsilis cardium.

Polycyclic musk fragrances are common additives to many consumer products. As a result of their widespread use and slow degradation rates, they are widely found in aquatic environments. This study reports on the lethal and sublethal toxicity of the polycyclic musks AHTN (Tonalide) and HHCB (Galaxolide) to glochidial (larval) and juvenile life stages of the freshwater mussel Lampsilis cardium (Rafinesque, 1820). In glochidia, 24-h median lethal concentrations (LC50s) ranged from 454 to 850 microg AHTN/L and from 1000 to >1750 microg HHCB/L (water solubility). Results for 48-h tests were similar to the 24-h tests. In 96-h tests with juveniles, we did not observe a dose-response relation between mortality and either musk. However, the growth rate was reduced by musk exposure. The median effective concentrations (EC50s, based on growth) were highly variable and ranged from 108 to 1034 microg AHTN/L and 153 to 831 microg HHCB/L. While all adverse effects occurred at concentrations that are much greater than those reported in natural waters (low microg/L to ng/L), these results indicate the potential for adverse effects on these long-lived organisms from exposure to synthetic musk fragrances.

Personality of dental students in two dental schools in the United Kingdom and in Ireland.

The personality characteristics of students from two dental schools, one in the United Kingdom which admitted students using interviews, and one in Ireland which accepted students solely on examination results, were assessed using the short form of the Eysenck Personality Questionnaire. Results were compared with norms for age and sex. Personality scores of students from the Irish dental school were not significantly different from normal scores. Female and male students from the United Kingdom school scored higher than would be expected on extraversion, and male students from the same school scored lower than would be expected on neuroticism. The differences in personality between the two schools may be explained by the different methods of admission.

Intestinal migrating myoelectric complexes in rats with acute pancreatitis and bile duct ligation.

Intestinal migrating myoelectric complexes (MMC) were studied in rats subjected to common bile duct ligation. Four pairs of bipolar electrodes were implanted on the jejunum and the ileum of 21 rats. Animals were allowed to recover 7 days before electrical recordings were made. Bile duct ligation at the entrance to the duodenum (low) or above the pancreas (high) or sham operation was performed. MMCs were recorded before and 48 and 72 hr after the operation in each animal. MMC intervals were unchanged following high ligation or sham operation. However, 48 hr after low bile duct ligation, the MMC interval (20.6 +/- 2.5 min) was significantly prolonged compared with that before ligation (14.0 +/- 1.2 min). Further prolonged intervals (28.4 +/- 4.2 min) were observed 72 hr after the ligation. There were no significant differences among the slow wave frequencies in any group of animals, being in the range of 34.1 +/- 1.1 to 36.3 +/- 1.0 cycles/min. Thus, the MMC pattern in this rat model may be affected by the development of acute pancreatitis. The mechanism(s) responsible for altering the MMC pattern are not known; however, hepatic biliary secretion alone does not appear to play a primary role.

Psychometric properties of the Social Training Achievement Record (the STAR profile).

Seven hundred and sixty-eight Social Training Achievement Records were collected independently in two settings during routine assessment of mentally handicapped people, mostly adults in hospital. All scales and total scores were highly internally consistent. Factor analysis on one sample yielded two factors named General Adaptive Behaviour and Community and Equipment Skills. This factor structure was replicated on the second sample. This factor solution is highly similar to that reported for the Adaptive Behavior Scale (Nihira, 1976). Two new scales were derived on the basis of these factor analyses which were also highly internally consistent. Parallel forms of these scales were also satisfactorily developed. Total scores and scores on the two new scales were adequate in routine clinical practice and showed good concurrent and criterion group validities. Reliabilities of individual items were less satisfactory. Suggestions for future developments of this scale are made.

Age differences in the rating of life-stress events: does contextual detail make a difference?

Twenty-four young (20 to 25 years) and 24 elderly (61 to 81 years) subjects rated the short-term (ST) and long-term (LT) threat of 36 life-events drawn from a community study of elderly people. Subjects were presented either with full contextual detail about the respondent and the event or with an edited version in which only a basic outline of the event was presented. Assignment of subjects to conditions was random. Agreement of subjects within and between groups as to what events were threatening was high and the untrained groups were also in close agreement with the consensus ratings of a trained panel. There were no significant main effects of age or contextual condition. It is concluded that the concept of the 'threat' of an event is generalizable over samples. Analysis of a significant age x context interaction showed that only young subjects rating LT threat were affected by contextual condition. Events supplied with context were rated by them as less threatening than those presented in outline. Some evidence was found to support the view that there may be age differences in the perceived impact of an event over time.