[Perceived severity of cancer and therapeutic pluralism among medical oncologists at the Yaoundé General Hospital]. / Perception de la gravité de la maladie cancéreuse et pluralisme thérapeutique en oncologie médicale à l'Hôpital Général de Yaoundé.

Introduction: cancer is a potentially serious disease. The announcement of a cancer diagnosis is bad news. This diagnosis is experienced differently from one person to the next. Patient's behaviour and compliance reflects specific behaviors of relatives. Alternative treatments are commonly used in oncology in some African countries. The purpose of this study was to establish cancer patients' experience, the extent of the use of alternative treatments and factors influencing their choices. Methods: we conducted a descriptive study at the Yaoundé General Hospital from December 2019 to May 2020. The study included patients over 18 years of age treated for cancer, who had been undergoing chemotherapy for at least three months and who agreed to complete the questionnaire. Results: the interview involved 122 patients. Sex ratio was 1/1. The average age of patients was 45 years; 38.5% of patients thought that cancer is a very serious disease, 24% were desperate for diagnosis, 61% thought that recovery would be very slow. Pluralists in our sample accounted for 59.8%. Conclusion: cancer patients and their relatives generally perceive cancer as serious. Patients experience a feeling of sudden and intense anxiety when they are diagnosed with cancer. Therapeutic pluralism is a frequent practice.

[An unusual case of condylomata acuminata identified in the nasal cavity of a patient living in Yaoundé, Cameroon: a clinical report and literature review]. / Localisation exceptionnelle de condylomes acuminés dans les fosses nasales d'une patiente vivant à Yaoundé, Cameroun: cas clinique et revue de la littérature.

Condylomata acuminata are sexually transmitted lesions caused by human papillomavirus. They mainly occur in the anogenital area and exceptionally in the nasal cavity. We here report a new case of uncommon detection. The study involved a HIV-positive female patient with recurrence of vulvar condylomata acuminata treated in the department of gynecology. She was referred to our department with pink masses in the nasal cavity preventing nasal breathing and evolving over several weeks. Clinical examination and computerized tomography (CT) scan suggested condylomata. Surgical treatment was performed under general anesthesia and endoscopic control; the histological examination showed condylomata acuminata. The postoperative course was simple, with no recurrence after 6 months of follow-up. Condylomata acuminata in the nasal cavity are rare or even exceptional; only very few cases have been described in the literature. They commonly affect young subjects with or without HIV infection, having sexual risk behavior and can occur in several areas, in particular in the genital area. In this case, nasal lesions could result from hand-mediated transfer. Surgical treatment is effective and long-term follow-up is essential to treat possible recurrences.

Sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor with no previous asbestos exposure.

Sarcomatoid malignant peritoneal mesothelioma is the rarest and most lethal form of peritoneal mesothelioma. We present the case of a sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor in a 54-year-old female with no previous asbestos exposure. This clinical presentation is extremely rare and is the first documented in Cameroon.

Intra- and interobserver reproducibility of grading of helicobacter pylori gastritis according to the updated sydney system

Aims. To study the intra- and interobserver reproducibility of Sydney System amongst pathologists in Cameroon as Sydney System gradation has not gained enough confidence in African pathologists. Methods. We performed a descriptive study including 100 patients who benefited from gastric biopsy by endoscopy. These biopsy specimens were stained with hematein and eosin and modified Giemsa; and read independently using the same microscope by two pathologists with four years experience and no experience with the updated Sydney System. Gastritis was graded according to the updated Sydney System. Levels of intra- and interobserver reproducibility were assessed using the unweighted kappa coefficient. Results. The intraobserver reproducibility of gradation of Helicobacter pylori density; activity; chronic inflammation; atrophy; and intestinal metaplasia showed respective values of kappa: 0.63; 0.34; 0.61; 0.48; and 0.82 for one observer against 0.42; 0.005; 0.41; 0.31; and 0.72 for the other. Interobserver reproducibility kappa values were; respectively; 0.41; 0.18; 0.57; 0.58; and 0.82. Conclusion. Results are encouraging but experience in the updated Sydney System should be improved. The later should be introduced as a means to grade and classify gastritis in Cameroon and African countries

Cornual molar ectopic pregnancy: a case report with difficult management in poor resources settings

Molar pregnancy is a rare entity and ectopic location of pregnancy in the uterine horn represents the least frequent site of implantation. This paper presents a rare case of molar cornual ectopic pregnancy at advanced gestational age with a particular difficulty in diagnosis and management. A 35-year-old woman; gravida 4 para 3 with a history of 12 weeks amenorrhea; was operated for presumed ruptured ectopic pregnancy. Per-operative findings showed swollen villi in clusters that looked like bunches of grapes; characteristic of a complete hydatiform mole; located at the left horn of the uterus. Histopathologic examination confirmed the diagnosis. Bleeding could not be controlled with suturing and hysterectomy was eventually done. Although rare; molar pregnancy can be ectopic. If it is located at the uterine horn; bleeding may be difficult to control if at a gestational age of 12 weeks or more