RESUMO
We report what is to our knowledge the first observation of a time-resolved diffusing wave spectroscopy (DWS) signal recorded by transillumination through a thick turbid medium: the DWS signal is measured for a fixed photon transit time, which opens the possibility of improving the spatial resolution. This technique could find biomedical applications, especially in mammography.
Assuntos
Mama/citologia , Interpretação de Imagem Assistida por Computador/métodos , Mamografia/métodos , Nefelometria e Turbidimetria/métodos , Espectrofotometria Infravermelho/métodos , Difusão , Desenho de Equipamento , Análise de Falha de Equipamento , Mamografia/instrumentação , Nefelometria e Turbidimetria/instrumentação , Imagens de Fantasmas , Projetos Piloto , Espectrofotometria Infravermelho/instrumentaçãoRESUMO
We presented theoretical and experimental demonstrations of the possibilities of performing time-resolved diffusing wave spectroscopy: We successfully registered field fluctuations for selected photon path lengths that can surpass 300 transport mean free paths. Such performance opens new possibilities for biomedical optics applications.
RESUMO
We present time-resolved measurements by speckle interferometry of the light scattered by a liquid medium. Measurements were performed by use of reflectance geometry and are compared with results obtained in the same conditions with a femtosecond laser and a streak camera. The setup was also tested in vivo on the forearm of a human volunteer to demonstrate the potential utility of such a setup for biomedical applications.
