Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 16 de 16
Filtrar
Mais filtros










Intervalo de ano de publicação
1.
Int J Gen Med ; 16: 1695-1703, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37187590

RESUMO

Purpose: This study was conducted to evaluate the results of conservative management of blunt splenic trauma according to the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) in 2018 by embolization. Methods: This observational study included 50 patients (42 men and 8 women) with splenic injury who underwent multidetector computed tomography (MDCT) and embolization. Results: According to the 2018 AAST-OIS, 27 cases had higher grades than they did according to the 1994 AAST-OIS. The grades of two cases of grade II increased to grade IV; those of 15 cases of grade III increased to grade IV; and four cases of grade IV increased to grade V. As a result, all patients underwent successful splenic embolization and were stable at discharge. No patients required re-embolization or conversion to splenectomy. The mean hospital stay was 11.8±7 days (range, 6-44 days), with no difference in length of hospital stay among grades of splenic injury (p >0.05). Conclusion: Compared with the AAST-OIS 1994, the AAST-OIS 2018 classification is useful in making embolization decisions, regardless of the degree of blunt splenic injury with vascular lacerations visible on MDCT.

2.
Sensors (Basel) ; 23(3)2023 Jan 24.
Artigo em Inglês | MEDLINE | ID: mdl-36772363

RESUMO

An adjustable 4×4 antenna array with electrical beam steering and polarization control is presented. Here, adjustability means the ability to correct the beam steering angle post-calibration. The objective is to improve the steering accuracy which is critical in point-to-point communication as inaccuracy will cause transmission failure due to a missed target. The accuracy is enhanced by adjusting the beam steering angle in beamforming calculations. To execute this, the system is calibrated by measuring several unit cells of a partial 4×4 array structure at different voltage bias points and calculating an average model of the phase shift profile. This reduces the phase error from variations between components and robust beam steering is achieved. This technique is utilized in far-field measurements, and fairly accurate initial beam steering angles are achieved at 3 GHz. The accuracy is further improved by over or under steering the desired angle in the beamforming calculations to finally achieve the steering angle of interest with an accuracy of 2∘. Overall, the main beam is incrementally steered from 0∘ to 45∘ with the gain ranging from 4.7 dB to 2.8 dB. The polarization control is also demonstrated in horizontal and vertical directions for a linearly polarized wave.

3.
Appl Radiat Isot ; 182: 110127, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35176611

RESUMO

The results of 226Ra activity concentration measurements in 50 soil and groundwater samples in Ninh Son region, Vietnam were evaluated in the present study. Average activity concentration in the soils was significantly higher than the worldwide average concentration in soils published by UNSCEAR, 2008. 90% of groundwater samples had concentrations of 226Ra that were higher than the USEPA drinking water standard. The results showed that there was a linear correlation between the 226Ra radioactivity in the soils and the concentration of 226Ra in the groundwater samples. The procedure for removal of 226Ra from soil and groundwater samples was built upon the chemistry behavior of radium. 226Ra in contaminated groundwater samples was removed by using MnO2 fiber. The removal efficiency of 226Ra reached ∼ 91% for the groundwater samples and ∼ 70% for the soil samples. Chemical removal of 226Ra from soils was investigated using a three-step extraction procedure (Easily leachable and exchangeable, Acid-reducible, and Oxidisable-organic). A moderate mobility of 226Ra (22-52%) was noted and mainly found in acid-reducible fractions, which suggests that 226Ra is mainly bound to Fe/Mn oxides and hydroxides. A multiple regression indicates that the 226Ra removal efficiency appears to be significantly dependent on Fe/Mn and organic matter content.


Assuntos
Água Subterrânea/química , Rádio (Elemento)/análise , Poluentes Radioativos do Solo/análise , Solo/química , Poluentes Radioativos da Água/análise , Purificação da Água/métodos , Concentração de Íons de Hidrogênio , Óxido de Magnésio , Vietnã , Abastecimento de Água
4.
ACS Synth Biol ; 10(11): 3139-3147, 2021 11 19.
Artigo em Inglês | MEDLINE | ID: mdl-34762391

RESUMO

In this paper, we report a stepwise RNA-primed RNA polymerization method for the site-specific incorporation of multiple fluorescent moieties into RNA, mediated by an RNA polymerase. A screen of several RNA polymerases revealed that T7 RNA polymerase was the only one that functioned in the RNA-primed RNA polymerization. In the first fluorescence labeling step, a fluorescent rUthioTP residue was incorporated directly into the RNA using T7 RNA polymerase; the second fluorescence labeling step was performed using a post-labeling strategy: directly introducing an rUamiTP residue into RNA, using T7 RNA polymerase, and then reacting with ylidenemalononitrile enamine (P3). The whole process for the site-specific introduction of the multiple labeled moieties was performed through stepwise RNA-primed RNA polymerization. Interestingly, the resulting multiple-labeled RNA exhibited fluorescence resonance energy transfer (FRET) between the two fluorescent labels in the RNA. We optimized the FRET-breaking point in the RNA by changing of distance between the two fluorescent labels and then used this property for the detection of the structural change of the RNA. The FRET signal increased in intensity upon the transformation of the RNA from a single-strand structure to the G-quadruplex. This approach for site-specific FRET labeling into RNA using RNA polymerase suggests the possibility of performing other diverse site-specific modifications at predefined positions in RNA.


Assuntos
RNA Polimerases Dirigidas por DNA/genética , RNA/genética , Transferência Ressonante de Energia de Fluorescência/métodos , Corantes Fluorescentes/metabolismo , Quadruplex G , Polimerização , Proteínas Virais/genética
6.
J Environ Manage ; 271: 111001, 2020 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-32778287

RESUMO

In topsoils, the activity concentrations of natural radionuclides (hereafter NRs) increase due to the addition of NRs from fertilizers, irrigation water, and air dust pollution. On the other hand, various physical-chemical and environmental processes such as radioactive decay, volatilization, leaching, erosion, and plant uptake were responsible for the decrease of the activity concentrations of NRs in the topsoils. In this study, behaviours of 40K, 210Pb, 226Ra, 238U, and 232Th in topsoils were modelled by the CEMC soil model and the HYDRUS-1D model. An exponential equation was proposed for estimating the accumulation rates of these radionuclides in the topsoils. Long-term accumulation of radionuclides was assessed for water spinach (Ipomoea Aquatica Forssk.) soil (hereafter VES) and rice (Oryza sativa L.) soil (hereafter RIS). We found that the current agricultural practices caused the increase of 40K activity concentration in the water spinach soil, and 40K, 210Pb, 226Ra, and 232Th activity concentrations in the rice soil. The accumulation rates of radionuclides were in the order 238U < 232Th < 226Ra < 210Pb < 40K. 25 years of cultivation with water spinach can increase/decrease + (165 ± 6) Bq of 40K, - (8.2 ± 0.7) Bq of 210Pb, - (4.3 ± 0.2) Bq of 226Ra, - (7 0.3 ± 0.3) Bq of 238U, and - (1.8 ± 0.1) Bq of 232Th in 1 kg soil. For rice cultivation, these values are + (1004 ± 39), + (3.3 ± 0.2), + (3.0 ± 0.2), - (5.1 ± 0.3), (2.2 ± 0.1) Bq kg-1 for 40K, 210Pb, 226Ra, 238U, and 232Th, respectively.


Assuntos
Ipomoea , Oryza , Monitoramento de Radiação , Poluentes Radioativos do Solo/análise , Chumbo , Radioisótopos/análise , Spinacia oleracea , Vietnã , Água
7.
Environ Sci Pollut Res Int ; 27(25): 31812-31826, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32504433

RESUMO

Groundwater is a major source of drinking water and agricultural water in some regions of the world. However, it contains a high level of 226Ra that is potentially hazardous to human health and the environment. Normally, the activity concentration of 226Ra in groundwater is determined to assess the quality of groundwater that can be used as drinking water. There are few studies on the accumulation of 226Ra in the agricultural soil due to irrigation with groundwater. In this study, levels of 226Ra were determined on over 60 groundwater samples collected from the public water supply wells in Phu Yen province, Vietnam. Besides assessment of the health risks to population due to drinking groundwater samples, the impact of groundwater irrigation to the maize field in the study area was studied. For this purpose, two chemical fate models were applied and the comparison of their results was performed. Based on the model assessments, we predicted that the present agricultural practices increased the 226Ra activity concentration in the maize soil, and the level of 226Ra activity concentration in the topsoil can exceed the recommended level at 11.4 years of the present agricultural practices on the maize soil.


Assuntos
Água Subterrânea , Poluentes Químicos da Água/análise , Irrigação Agrícola , Monitoramento Ambiental , Humanos , Solo , Vietnã , Abastecimento de Água , Zea mays
8.
Chem Commun (Camb) ; 56(21): 3199-3202, 2020 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-32068200

RESUMO

We have developed a propargylamine-selective dual fluorescence turn-on system, using ylidenemalononitrile enamines, for post-synthetic DNA labeling, allowing the direct monitoring of DNA using dual emission in living cells.


Assuntos
DNA/química , Fluorescência , Corantes Fluorescentes/síntese química , Pargilina/análogos & derivados , Propilaminas/química , Linhagem Celular Tumoral , Corantes Fluorescentes/química , Humanos , Estrutura Molecular , Imagem Óptica , Pargilina/química , Coloração e Rotulagem
9.
Analyst ; 144(10): 3216-3220, 2019 May 13.
Artigo em Inglês | MEDLINE | ID: mdl-30984925

RESUMO

A DSN-RNAse-TdT-T7 exo probing system allows the detection of miRNA 21 with very high sensitivity (LOD = 2.57 fM) and selectivity-the result of (i) avoiding the false-positive signal from miRNA reacting with TdT polymerase and (ii) signal amplification occurring through a FRET-breaking mechanism involving T7 exo.


Assuntos
DNA Nucleotidilexotransferase/química , Exodesoxirribonucleases/química , MicroRNAs/sangue , Ribonucleases/química , Bacteriófago T7/enzimologia , Sondas de DNA/síntese química , Sondas de DNA/genética , DNA de Cadeia Simples/síntese química , DNA de Cadeia Simples/genética , Transferência Ressonante de Energia de Fluorescência/métodos , Corantes Fluorescentes/química , Humanos , Limite de Detecção , MicroRNAs/genética , Técnicas de Amplificação de Ácido Nucleico , Hibridização de Ácido Nucleico , RNA Mensageiro/genética
10.
Chem Commun (Camb) ; 55(15): 2158-2161, 2019 Feb 14.
Artigo em Inglês | MEDLINE | ID: mdl-30675606

RESUMO

We have developed a new method, a step-wise approach with polymerase, for site-specific incorporation of multiple units of functional nucleotides into DNA to form hairpin secondary structures. The fluorescence of the resulting DNA incorporating the functional nucleotides varied upon transitioning from single-strand to hairpin and duplex structures.


Assuntos
DNA Polimerase Dirigida por DNA/metabolismo , DNA/metabolismo , Nucleotídeos/metabolismo , DNA/química , Corantes Fluorescentes/química , Conformação de Ácido Nucleico , Nucleotídeos/química , Espectrometria de Fluorescência , Repetições de Trinucleotídeos/genética
11.
Ecotoxicol Environ Saf ; 169: 216-224, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30448704

RESUMO

Fate modelling of artificial radionuclides (ARs) in top soils are necessary to assess the radiological effects to population. Among ARs, 137Cs, 90Sr and 131I are very important since the large abundances in the environment. In this study, the fates of 137Cs, 90Sr and 131I in the surface soil layers were simulated by the soil model which was developed by the Canadian Centre for Environmental Modelling and Chemistry (CEMC). The scenario that 137Cs, 90Sr and 131I contaminated in topsoil in the exclusion of Fukushima Daiichi nuclear power plant (NPP) accident was evaluated. The results show the expected time for the minimum hazardous level of exposure. It is 115.5 days after the exposure, when the total effective dose is 1 mSv y-1 in which 0.46 mSv y-1 from ingestion and 0.54 mSv y-1 from gamma exposure. Hazard levels due to exposure progresses are varied in order gamma exposure (82.14%) > ingestion (17.47%) > inhalation (0.39%). The hazard levels from radionuclides are varied in order 137Cs (63.34%) > 131I (33.48%) > 90Sr (3.18%).


Assuntos
Radioisótopos de Césio/análise , Radioisótopos do Iodo/análise , Modelos Teóricos , Monitoramento de Radiação/métodos , Poluentes Radioativos do Solo/análise , Radioisótopos de Estrôncio/análise , Raios gama , Meia-Vida , Solo/química , Vietnã
12.
J Environ Radioact ; 193-194: 27-35, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30179759

RESUMO

Field experiments on soil radon and radium concentrations were carried out in eighteen locations in Ho Chi Minh City, Vietnam. Soil radon depth profiles (10-100 cm) of loam, sand and clay soil samples in the rainy season were measured using RAD7 radon detector. Mean concentrations of 222Rn and 226Ra were found to be 28.6 ±â€¯2.0 Bq.kg-1 and (1.56 ±â€¯0.06) × 104 Bq.m-3 in clay soil while they are 31.2 ±â€¯2.5 Bq.kg-1 and (1.15 ±â€¯0.05) × 104 Bq.m-3 in loam soil. They are 30.7 ±â€¯2.0 Bq.kg-1 and (9.37 ±â€¯0.52) × 103 Bq.m-3 in sandy soil, respectively. Values of radon diffusion length and diffusion coefficient for different soils were obtained using semi-empirical fit method linked to the poor diffusion of gas in clay soil (0.2 × 10-6 m2 s-1), the moderate diffusion coefficient (0.9 × 10-6 m2 s-1) in loam and good diffusion of radon gas in sandy soil (1.4 × 10-6 m2 s-1). An unexpectedly unclear linear relation was found between soil radon concentration and radium content. The grain size smaller than 0.1 mm was dominant reason for the lowest (0.15 ±â€¯0.01) and highest (0.40 ±â€¯0.03) values emanation coefficient for sand and clay soil, respectively. A strong positive correlation was found between radon concentration and soil pH level leads to soil pH is an indirect dynamic parameter affecting the migration of radon in soil.


Assuntos
Monitoramento de Radiação , Radônio/análise , Chuva , Poluentes Radioativos do Solo/análise , Rádio (Elemento)/análise , Estações do Ano , Solo/química , Vietnã
13.
J Healthc Eng ; 2018: 3654210, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30631411

RESUMO

Minimally invasive surgery (MIS) minimizes the surgical incisions that need to be made and hence reduces the physical trauma involved during the surgical process. The ultimate goal is to reduce postoperative pain and blood loss as well as to limit the scarring area and hence accelerate recovery. It is therefore of great interest to both the surgeon and the patient. However, a major problem with MIS is that the field of vision of the surgeon is very narrow. We had previously developed and tested an MIS panoramic endoscope (MISPE) that provides the surgeon with a broader field of view. However, one issue with the MISPE was its low rate of video stitching. Therefore, in this paper, we propose using the region of interest in combination with the downsizing technique to improve the image-stitching performance of the MISPE. Experimental results confirm that, by using the proposed method, the image size can be increased by more than 160%, with the image resolution also improving. For instance, we could achieve performance improvements of 10× (CPU) and 23× (GPU) as compared to that of the original method.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Algoritmos , Animais , Endoscopia/métodos , Imagens de Fantasmas , Gravação em Vídeo
14.
Appl Radiat Isot ; 105: 219-224, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26334782

RESUMO

The results of (222)Rn and (226)Ra activity measurements in drinkable water supplies of the Thu Duc region in Ho Chi Minh City, Vietnam, are presented in this paper. The measurements were performed using a RAD 7 radon detector manufactured by Durridge Company, Inc. Mean concentrations of (222)Rn and (226)Ra were found to be 0.11±0.01Bql(-1) and 0.11±0.02Bql(-1) in 14 drinking water samples. They are 0.12±0.01Bql(-1) and 0.10±0.02Bql(-1) in 15 tap water samples, respectively. The mean (222)Rn concentration of 1.40±0.03Bql(-1) in the 20 groundwater samples of this study is also lower than the WHO advised level of 100Bql(-1). Fifty percent of groundwater samples analysed have (226)Ra levels in excess of the USEPA recommended maximum contaminant level of 0.185Bql(-1). The occurrence of elevated concentrations of (226)Ra in groundwater samples was explained by pH and alkaline conditions.

15.
Artigo em Vietnamês | WPRIM (Pacífico Ocidental) | ID: wpr-4509

RESUMO

Introduction: This action research aimed to make a context-specific and gender-sensitive interventions. Intervention activities was participatory to decrease the barriers to the use of maternal care and family planning (MCFP) services by the disadvantaged Kinh people and Catu ethnic minority people in the mountainous area of Nam Dong District in Central Vietnam. Intervention also aimed to improve communal MCFP services prioritized to training effective communication skills for communal health centers' staff and village health workers. Methods: 2 surveys were conducted before and after intervention among 7 poor communes using a random sample of total 840 mothers with at least one child under the age of 5 years. These data were supplemented by interviews with key informants, focus group discussions and observations. Statistical tests and measurement of effective index (EI) were used in data analysis. Results: - Women having ANC and delivery at local MCFP service were increasing 97.6% and 50% in year 2005 as compared with 86.9% and 31% respectively in year 2003. Midwives paid much attention to non-verbal communication as well as to counseling using demonstrative pictures. - There were a clear evidence of significantly increasing the mother's knowledge of MCFP such as local MCFP service availability, benefit of ANC (p=3 times was significantly increasing (EI=11.98%, p<0.01). - The percentage of mothers who delivered at home was slow down to 19.4% as compared with before intervention was 45.2% respectively (EI= 64.20%, p<0.001) Conclusion: Intervention model was considerably successful in using context-specific and gender sensitive approaches. It contributed to meeting an urgent need for the MCFP services to build both clinical capacity and health promotion activities in a way that is gender sensitive, knowledge on of traditional practices and accessible by both illiterate and minority language speaking people.


Assuntos
Serviços de Saúde Materna , Serviços de Planejamento Familiar , Comportamento Materno
16.
Artigo em Vietnamês | WPRIM (Pacífico Ocidental) | ID: wpr-4287

RESUMO

Intra-cranial hemorrage is a serious condition in infants can result in significant morbidity and mortality in developing countries. 680 infants with intracranial haemorrhage have symptoms for 30-60 days (86.2%). Sex ratio between boys and girls was 3/1. The laboratory findings as followed: prolongation of PT, APTT (94,7%), diminution of factors II,VII,IX in 80% of cases. Clinical manifestations are acute anemia (99.1%), distubance of consiousness (100%);100% have some kind of seizures; 91% in bulging of the anterior fontanel. Subarachnoid hemorrhage was major condition in 90.1% of patients, but allways combined with other lesions. The mortality was 14.7% and survived children had severe psycho-neurological sequelae. Intra-cranial hemorrhagic disease in infants has the characteristics of vitamin K deficiency. The haemorrhagic lesions are diverse and complex. Disease caused high mortality as well as high sequella rates.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...