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Nat Prod Res ; 36(19): 4892-4897, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33813958

RESUMO

A new steroidal saponin, torvoside R (1), was isolated along with torvoside Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts of Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (1 - 3) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, and T24 cancer cell lines with IC50 values ranging from 14.18 to 89.31 µg/mL.


Assuntos
Saponinas , Solanum , Cloreto de Metileno , Estrutura Molecular , Componentes Aéreos da Planta , Saponinas/química , Saponinas/farmacologia , Solanum/química , Esteroides/química , Esteroides/farmacologia
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