ABANICCO: A New Color Space for Multi-Label Pixel Classification and Color Analysis.

Classifying pixels according to color, and segmenting the respective areas, are necessary steps in any computer vision task that involves color images. The gap between human color perception, linguistic color terminology, and digital representation are the main challenges for developing methods that properly classify pixels based on color. To address these challenges, we propose a novel method combining geometric analysis, color theory, fuzzy color theory, and multi-label systems for the automatic classification of pixels into 12 conventional color categories, and the subsequent accurate description of each of the detected colors. This method presents a robust, unsupervised, and unbiased strategy for color naming, based on statistics and color theory. The proposed model, "ABANICCO" (AB ANgular Illustrative Classification of COlor), was evaluated through different experiments: its color detection, classification, and naming performance were assessed against the standardized ISCC-NBS color system; its usefulness for image segmentation was tested against state-of-the-art methods. This empirical evaluation provided evidence of ABANICCO's accuracy in color analysis, showing how our proposed model offers a standardized, reliable, and understandable alternative for color naming that is recognizable by both humans and machines. Hence, ABANICCO can serve as a foundation for successfully addressing a myriad of challenges in various areas of computer vision, such as region characterization, histopathology analysis, fire detection, product quality prediction, object description, and hyperspectral imaging.

Nonlinear Image Registration and Pixel Classification Pipeline for the Study of Tumor Heterogeneity Maps.

We present a novel method to assess the variations in protein expression and spatial heterogeneity of tumor biopsies with application in computational pathology. This was done using different antigen stains for each tissue section and proceeding with a complex image registration followed by a final step of color segmentation to detect the exact location of the proteins of interest. For proper assessment, the registration needs to be highly accurate for the careful study of the antigen patterns. However, accurate registration of histopathological images comes with three main problems: the high amount of artifacts due to the complex biopsy preparation, the size of the images, and the complexity of the local morphology. Our method manages to achieve an accurate registration of the tissue cuts and segmentation of the positive antigen areas.