Assuntos
Neoplasias da Mama/patologia , Carcinoma/terapia , Quimioembolização Terapêutica/efeitos adversos , Toxidermias/etiologia , Neoplasias Hepáticas/terapia , Antibióticos Antineoplásicos/administração & dosagem , Carcinoma/secundário , Doxorrubicina/administração & dosagem , Feminino , Humanos , Neoplasias Hepáticas/secundário , Microesferas , Pessoa de Meia-Idade , Pele/irrigação sanguíneaRESUMO
Sclerosing sweat duct carcinoma is a rare, locally aggressive adnexal tumor that frequently occurs on the face of middle-aged adults, invades deeply, and has a propensity to recur. We report a rare instance of sclerosing sweat duct carcinoma occurring in a 6-year-old African American child and review the literature of this infrequently observed neoplasm.
Assuntos
Negro ou Afro-Americano , Carcinoma de Apêndice Cutâneo/etnologia , Carcinoma de Apêndice Cutâneo/patologia , Invasividade Neoplásica/patologia , Neoplasias das Glândulas Sudoríparas/etnologia , Neoplasias das Glândulas Sudoríparas/patologia , Biópsia por Agulha , Carcinoma de Apêndice Cutâneo/cirurgia , Criança , Feminino , Seguimentos , Humanos , Imuno-Histoquímica , Cirurgia de Mohs , Medição de Risco , Cirurgia de Second-Look , Neoplasias das Glândulas Sudoríparas/cirurgia , Fatores de Tempo , Resultado do TratamentoRESUMO
Galli-Galli disease is a rare variant of the genodermatosis Dowling-Degos disease with the histologic finding of acantholysis. We present the case of a patient who presented with reticulated pigmentary changes in the flexures as well as a pruritic papular eruption and histologic features consistent with Galli-Galli disease. A literature search revealed 3 previous case reports of Galli-Galli disease. These case reports were reviewed and summarized, and the clinical and histologic presentations were compared with those of our patient. In addition, another case report of patients with similar clinical manifestations was found and is presented herein. The differential diagnosis of Galli-Galli disease includes classic Dowling-Degos disease, transient acantholytic dermatosis, Darier's disease, and epidermolysis bullosa with mottled pigmentation. Galli-Galli disease is best considered a subtype of Dowling-Degos disease with clinical and histologic features similar to transient acantholytic dermatosis.
Assuntos
Acantólise/patologia , Dermatite/patologia , Transtornos da Pigmentação/patologia , Acantólise/diagnóstico , Dermatite/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Transtornos da Pigmentação/diagnósticoRESUMO
Of the diseases within the spectrum of the juvenile idiopathic inflammatory myopathies, juvenile dermatomyositis (JDM) is the most common. As the name implies, JDM affects the muscles and skin most commonly, but can involve other organ systems as well. Dermatologic manifestations often precede other signs and symptoms by months or even years and frequently are the primary reason the patient seeks medical attention. In the case presented here, a 3-year-old boy initially developed a hand rash that brought him to his primary care physician. By the time muscle weakness had developed, the patient had already been evaluated for dermatomyositis and therapy had been initiated. An understanding of these early clinical findings will enable physicians to make a timely diagnosis and commence therapy promptly in order to prevent life-threatening sequelae of the disease.
