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1.
Nature ; 457(7231): 873-6, 2009 Feb 12.
Artigo em Inglês | MEDLINE | ID: mdl-19212408

RESUMO

Continental rift zones are long, narrow tectonic depressions in the Earth's surface where the entire lithosphere has been modified in extension. Rifting can eventually lead to rupture of the continental lithosphere and creation of new oceanic lithosphere or, alternatively, lead to formation of wide sedimentary basins around failed rift zones. Conventional models of rift zones include three characteristic features: surface manifestation as an elongated topographic trough, Moho shallowing due to crustal thinning, and reduced seismic velocity in the uppermost mantle due to decompression melting or heating from the Earth's interior. Here we demonstrate that only the surface manifestation is observed at the Baikal rift zone, whereas the crustal and mantle characteristics can be ruled out by a new seismic profile across southern Lake Baikal in Siberia. Instead we observe a localized zone in the lower crust which has exceptionally high seismic velocity and is highly reflective. We suggest that the expected Moho uplift was compensated by magmatic intrusion into the lower crust, producing the observed high-velocity zone. This finding demonstrates a previously unknown role for magmatism in rifting processes with significant implications for estimation of stretching factors and modelling of sedimentary basins around failed rift structures.

3.
Nephron ; 56(1): 40-3, 1990.
Artigo em Inglês | MEDLINE | ID: mdl-2172848

RESUMO

Infusion of an acidic amino acid, L-aspartate, to 10 volunteers resulted in transient, significant increases in urinary excretion of the major urinary trypsin inhibitor (p less than 0.002) and beta 2-microglobulin (p less than 0.02). Simultaneously with the proteinuria, urinary pH rose significantly (p less than 0.02). These changes appeared following the infusion and after the excretion of L-aspartate had reached the preinfusion level. Albumin excretion was unchanged indicating that the proteinuria was due to a decreased tubular reabsorption. The mechanism for the reversible tubular proteinuria is unknown. A simple pH effect due to alkalization of the urine was excluded, as NaHCO3 infusion was not followed by an increase in the excretion of the major urinary trypsin inhibitor and beta 2-microglobulin.


Assuntos
Ácido Aspártico/efeitos adversos , Proteinúria/induzido quimicamente , Adulto , Albuminúria/urina , Arginina/urina , Ácido Aspártico/administração & dosagem , Bicarbonatos/farmacologia , Feminino , Glicoproteínas/urina , Humanos , Infusões Intravenosas , Túbulos Renais Proximais/metabolismo , Masculino , Sódio/farmacologia , Bicarbonato de Sódio , Microglobulina beta-2/urina
4.
J Wildl Dis ; 25(4): 601-4, 1989 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-2810562

RESUMO

A large, adult male polar bear (Ursus maritimus) was found dead on a barrier island north of Prudhoe Bay, Alaska (USA), in June 1987. There were no external signs of trauma. A twisted distended stomach, distinctive parenchymal and fascial congestion, and significant difficulty in repositioning the anterior abdominal organs, indicated that gastric dilatation-volvulus (GDV) was the proximate cause of death. Polar bears frequently consume large quantities of food at one time and have large stomachs that are well adapted to periodic gorging. The scarcity of food in winter and early spring, combined with voluntary fasting and protracted vigorous activity during the breeding season in late spring may have predisposed this bear to GDV. The relationship between GDV and postprandial exercise emphasizes the need for a better understanding of how the present human invasion of arctic habitats may influence polar bear activities.


Assuntos
Carnívoros , Dilatação Gástrica/veterinária , Volvo Gástrico/veterinária , Ursidae , Animais , Dilatação Gástrica/complicações , Dilatação Gástrica/patologia , Masculino , Volvo Gástrico/complicações , Volvo Gástrico/patologia
6.
Acta Obstet Gynecol Scand ; 67(5): 437-40, 1988.
Artigo em Inglês | MEDLINE | ID: mdl-3218463

RESUMO

The contractibility and trainability of the pelvic floor were investigated during pregnancy and after vaginal delivery in 86 healthy primiparae. One group (TG) (n = 38) was instructed in training the pelvic floor from the 33rd week of pregnancy, whereas the other group (non-TG) (n = 39) was not. Both groups were measured by perineometry five times between 33rd-39th week of pregnancy and approximately 8 weeks after delivery. Half of the women were also measured 8 months post partum. At the beginning of the study both groups showed the same strength of the pelvic floor. 8 weeks and 8 months after delivery the TG were significantly (p less than 0.05) better able to contract the pelvic floor compared with the non-TG. 8 months post partum, the TG had regained the initial values of pelvic floor contraction as from 33rd week of pregnancy, whereas the non-TG had not. During pregnancy there was a better ability to contract the pelvic floor in the TG vis-à-vis the non-TG, though not significantly so. No difference in the course of delivery was observed, and the frequency of complications was the same in the two groups.


Assuntos
Complicações do Trabalho de Parto/prevenção & controle , Pelve/fisiologia , Gravidez/fisiologia , Adolescente , Adulto , Exercício Físico , Feminino , Humanos , Contração Muscular , Períneo/fisiologia , Estudos Prospectivos
7.
J Wildl Dis ; 18(4): 419-24, 1982 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-6296469

RESUMO

Sera from 57 wolves (Canis lupus) in three areas of Alaska were evaluated for evidence of previous exposure to infectious canine hepatitis virus (ICHV) and canine distemper virus (CDV). Fifty-four sera (94.7%) were positive for ICHV exposure and four (7%) were positive for CDV exposure. All four CDV-reacting wolves also had titres to ICHV. The relatively common occurrence of ICHV exposure may be due to the greater resistance of ICHV to chemical and physical agents and its transmissibility via the urine of infected animals. The ICHV titres observed could indicate enzootic pathogenic ICHV, or exposure to the mildly pathogenic vaccine strain of CAV-1 through contact with the urine of domestic dogs. If CAV-1 is the original source of exposure, the titres could represent an ICHV-protected wolf population.


Assuntos
Carnívoros , Cinomose/diagnóstico , Hepatite Infecciosa Canina/diagnóstico , Adenovirus Caninos/imunologia , Alaska , Animais , Anticorpos Antivirais/análise , Embrião de Galinha , Técnicas de Cultura , Efeito Citopatogênico Viral , Vírus da Cinomose Canina/imunologia , Cães , Testes de Neutralização
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