[CD11b and CD62L receptors expression on neutrophils after laparoscopic versus open cholecystectomy]. / Ekspresja receptorów CD11b i CD62L na powierzchni neutrofilów obojetnochlonnych po cholecystektomii laparoskopowej w porównaniu z cholecystektomia klasyczna.

UNLABELLED: The development of immunology correlated with surgery enables close recognition of multiple mechanisms responsible for more frequent complications observed after open surgical procedures than after minimally invasive operations. OBJECTIVE: Evaluation of selected elements of non-specific immunity in patients undergoing open cholecystectomy (OC) versus laparoscopic cholecystectomy (LC). MATERIAL AND METHODS: 30 postmenopausal females with non-complicated cholecystolithiasis were analysed. Both OC and LC was performed in 15 cases. Blood samples for an analysis were collected 24 hours before surgery and 24 and 72 hours postoperatively. Qualitative changes of neutrophils measured by the expression of CD11b and CD62L receptors on their surface without or with formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation were evaluated. RESULTS: The expression of CD11b and CD62L receptors show no significant changes in patients that underwent LC while patients that underwent OC had significant changes 24 hours postoperatively compared both with their preoperative values and values observed in patients after LC. CONCLUSION: The activation of neutrophils measured by changes of the expression of CD11b and CD62L receptors on their surface is connected with the magnitude of trauma and is only observed in patients after OC.

[The assessment of hepatic portal flow using Doppler's technique in patients after laparoscopic cholecystectomy]. / Ocena watrobowego przeplywu wrotnego metoda Dopplera u chorych po cholecystektomii laparoskopowej.

UNLABELLED: A decrease in hepatic portal flow was observed within two days after open cholecystectomy but such an analysis was not done for laparoscopic cholecystectomy. OBJECTIVE: To answer the following problems: 1. Is there any difference between the volume of hepatic portal flow in patients with cholecystolithiasis and without it. 2. Does hepatic portal flow change within two days after laparoscopic cholecystectomy compared with its preoperative value. MATERIAL AND METHODS: 30 patients without hepatic parenchyma diseases were qualified for the study (21 cases of cholecystolithiasis and 9 cases without cholecystolithiasis). In the group of patients with cholecystolithiasis a maximal portal velocity (Vmax) was measured by Doppler's technique and the diameter of the portal vein (D) before laparoscopic cholecystectomy and 1 and 2 days postoperatively. In the group without cholecystolithiasis these values were measured once. On the basis of Vmax a mean velocity (Vmean = 0.57 x Vmax) of portal flow was calculated. Using Vmean and D values a volume of portal flow was calculated. RESULTS: A mean hepatic portal flow volume in patients with cholecystolithiasis was 725+/-187 ml/min and without it 792+/-229 ml/min. The difference between these values was not statistically significant. No statistically significant differences were also found between values of preoperative and postoperative hepatic portal flow volume. CONCLUSIONS: No statistically significant difference was found between hepatic portal flow volume in patients with and without cholecystolithiasis. Hepatic portal flow does not change significantly within 2 days after laparoscopic cholecystectomy.