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1.
Artigo em Polonês | MEDLINE | ID: mdl-1670025

RESUMO

Investigations refer to the influence of fodder containing soil dust as one of the ingredients on morphology of the liver and the weight of experimental animals. Fodder containing soil dust was given to animals for various periods of time, the longest was 18 weeks. The results indicate that the intensity of morphological changes in the liver depends on the time of giving fodder. The observed changes referred to the vacuolization of hepatocytes, increase in the number of stellate cells Browicz-Kupffer, and apart from that lymphocytic infiltrations occurred locally. The weight of the experimental animals in the initial period (up to 3 weeks) decreased and then came back to normal in the later period, but in some animals it even decreased.


Assuntos
Poeira/efeitos adversos , Fígado/patologia , Solo , Administração Oral , Animais , Peso Corporal , Ratos , Ratos Wistar
3.
Gegenbaurs Morphol Jahrb ; 134(5): 763-72, 1988.
Artigo em Alemão | MEDLINE | ID: mdl-2852133

RESUMO

The effect of a single intratracheal application of the electroenergetic ashes and the soil dust on the liver cell was studied by means of the histoenzymatic methods for the determination of the activities of chosen hydrolases (AcP, E.C. 3.1.3.2. and ATP, E.C. 3.6.1.). The degree of the histochemical changes in hepatocytes depended on the kind of the applied dust and the trace elements' content in it. The activity's increase of the acid phosphatase and ATP-ase in each experimental group was observed, especially in the preparations collected from the animals were given the electroenergetic ashes.


Assuntos
Carvão Mineral , Poeira , Fígado/enzimologia , Monoéster Fosfórico Hidrolases/metabolismo , Solo , Fosfatase Ácida/metabolismo , Adenosina Trifosfatases/metabolismo , Animais , Animais de Laboratório/metabolismo , Histocitoquímica
4.
Med Pr ; 38(3): 175-83, 1987.
Artigo em Polonês | MEDLINE | ID: mdl-3670041

RESUMO

Histochemical studies of the activity of succinic dehydrogenase (SDH) and lactic dehydrogenase (LDH) in the pulmonary tissue of experimental animals which were given four coal ashes issued from different thermal-electric power stations: group VII--from the thermal-electric power station Siekierki (Warsaw), group VIII--from Wroclaw, group IX--from Leg (Cracow) and group XI--from Lódz, were carried out. In particular ash samples the content of trace elements and free silica was determined. The studies yield the following conclusions: 1. The activity of succinic dehydrogenase (SDH) and lactic dehydrogenase (LDH) was changed in the respiratory tract and pulmonary alveoli as a result of the electroenergetic ashes applied. 2. Changes in cytoenzymatic reactions of SDH and LDH vary with the type of ash applied. The greatest changes were found in group XI where the ashes contained almost doubled amount of such elements as Mn, Zn, Pb, Cu. 3. SDH exhibited a greater sensitivity to the effects of electroenergetic ashes, as compared to LDH. 4. Changes in the activity of the test SDH and LDH enzymes indicate disorders in oxydoreductory processes of cells.


Assuntos
Carvão Mineral , L-Lactato Desidrogenase/metabolismo , Pulmão/enzimologia , Succinato Desidrogenase/metabolismo , Aerossóis , Animais , Ativação Enzimática , Masculino , Centrais Elétricas , Ratos , Ratos Endogâmicos , Fatores de Tempo
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