RESUMO
The paper discusses the frequency of recurrences and metastases of endometrial carcinoma in 246 treated cases. Recurrences and metastases were identified in 41 (16.7% +/- 2.4) patients. A relationship between said frequency, on the one hand, and tumor size, extent of invasion through the myometrium and tumor differentiation, on the other, was established.
Assuntos
Recidiva Local de Neoplasia/epidemiologia , Neoplasias Uterinas/epidemiologia , Terapia Combinada , Feminino , Humanos , Histerectomia , Excisão de Linfonodo , Metástase Linfática , Invasividade Neoplásica , Recidiva Local de Neoplasia/etiologia , Recidiva Local de Neoplasia/patologia , Recidiva Local de Neoplasia/terapia , Estadiamento de Neoplasias , Cuidados Pós-Operatórios , Dosagem Radioterapêutica , Fatores de Tempo , Neoplasias Uterinas/etiologia , Neoplasias Uterinas/patologia , Neoplasias Uterinas/terapiaRESUMO
Clinical, cytologic, histologic and X-ray procedures were used in examining 120 patients with endometrial carcinoma. The results of pre- and intraoperative determination of clinical stage were compared in 65 cases of uterine extirpation with appendages and lymphadenectomy. Errors in preoperative identification of the extent of tumor expansion were made in 9 cases (13.8 +/- 4.3%). It was found that determinations of the site and expansion of tumor make the case for hystero-cervical-angiolymphography whereas identification of tumor pattern and degree of cell differentiation--for cytologic and histologic assays.
Assuntos
Adenocarcinoma/cirurgia , Histerectomia/métodos , Neoplasias Uterinas/cirurgia , Adenocarcinoma/diagnóstico , Adenocarcinoma/patologia , Feminino , Humanos , Excisão de Linfonodo , Metástase Linfática/diagnóstico por imagem , Linfografia , Estadiamento de Neoplasias , Neoplasias Uterinas/diagnóstico , Neoplasias Uterinas/patologiaRESUMO
A complex clinico-morphological study on the effect of 17-hydroxyprogesterone-capronate was conducted in a group of 75 patients aged 27-69 (stage I-15; stage II-41; stage III-17 and stage IV-2 cases). Total dose for the whole course was 8.0-10.0. All patients underwent surgery after hormonotherapy. Uterine cavity (before and during hormonotherapy) and resected material were examined histologically and cytologically. It was shown that 17-hydroxy-progesterone-capronate is capable of antitumor effect and even complete regression is possible. Most antitumor effect was observed at the initial stages of malignant disease and in cases of well-differentiated tumor. The data obtained may be used in deciding whether 17-hydroxyprogesterone-capronate should be administered in conjunction with other measures or separately.
