[Genetic characteristic of Haemophilus influenzae type B strains isolated in Russian regions].

AIM: Genotyping of Hib strains isolated in regions of Russia as well as characterization of genetic relations of typed strains with strains isolated in other areas. MATERIALS AND METHODS: Genetic characterization of 31 strains of Hib isolated in Russian regions during 2005-2008 was performed by multilocus sequence typing. RESULTS: Studied strains belonged to 11 variants of sequence types, 6 of which were described in previous studies, whereas other 5 were isolated for the first time during this study. The most common isolated strains were ST-92 (13 strains or 42%) and ST-6 (6 strains or 19%). Typed strains were distributed to two clonal complexes. Clonal complex "A1/A2" ("ST-6") incorporates all typed strains except ST-93 strain belonging to clonal complex "B1b" ("ST-93"). The majority of studied strains (19 or 61%) had difference from "central" sequence type of clonal complex, A1/A2 ("ST-6") on not more than one allele. CONCLUSION: Clonal structure of isolated strains is analogous to the one observed in Moscow and foreign strains.

[Diagnosis of autonomic-vascular dystonia in persons who participated in the liquidation of the effects of the Chernobyl AES accident]. / O diagnoze vegetativno-sosudistoi distonii u lits, prinimavshikh uchastie v likvidatsii posledstvii avarii na Chernobyl'skoi AES.

The diagnosis of autonomic-vascular dystonia caused by small doses of ionizing radiation can be made only on the basis of the objectivity, completeness, constructive and individual character of data. It gives an opportunity to reflect in the diagnosis cause/effect relationships, to define the main and supplementary factors of a pathological process and to show their interrelationships and interinfluence. It leads to the development of adequate therapeutic-rehabilitation tactics.

[Nervous system function in persons receiving irradiation at different dose ranges during the cleanup after the accident at the Chernobyl Atomic Electric Power Station]. / Sostoianie nervnoi sistemy u lits, poluchivshikh obluchenie v razlichnom diapazone doz pri likvidatsii posledstvii avarii na Chernobyl'skoi AES.

The paper is concerned with the results of neurological examination of 113 patients who developed acute radiation sickness of various degrees of severity during the elimination of the effects of the accident at the Chernobyl Nuclear Power Station. A clinical picture of neurological disorders at different periods of ARS was described. CNS specific and nonspecific lesions were defined.

[Status of the nervous system in victims of the accident at the Chernobyl atomic power plant]. / Sostoianie nervnoi sistemy u postradavshikh pri avarii na Chernobyl'skoi atomnoi élektrostantsii (ChAES).

Under neurological investigation were 113 patients with different degrees of severity of acute radiation disease (ARD). The patients were relatively evenly irradiated by beta- and gamma-rays as a result of CPP accident. The onset time and markedness of the signs of primary reaction were related to ARD severity. Early appearance of the signs of disturbances in the central nervous system functional state suggested a stronger affliction, malignant course and fatal outcome of the disease. Ii ARD patients with IV-th and III-rd degree of severity the syndromes observed were these: acute radiation encephalopathy immediately caused by the ionizing irradiation of the CNS, and a secondary radiation-toxic encephalopathy. The hemorrhagic lesioning of CNS and cerebral hemispheres were noted in terminal stages. In rehabilitation phases, neurasthenic and neurovascular syndromes appeared irrespective of the ARD severity.

[Course of ischemic heart disease in patients who have sustained a stroke]. / Techenie ishemicheskoi bolezni serdtsa u bol'nykh, perenesshikh mozgovoi insul't.

The state of the cardiovascular system was studied over time in 171 patients with a history of acute impairment of the brain circulation; 135 of them were suffering from coronary heart disease (CHD) (the study group) and 35 patients were free of CHD (the control group). The majority of the study group patients showed little if any clinical manifestations of CHD in the acute period of cerebral stroke. Five (3.7%) patients displayed small focal myocardial infarction on the ECG, two showed focal dystrophy of the myocardium, 71 (52.2%) patients had compromised coronary circulation and 47.5% of the patients had various disorders of rhythm and conductivity. The impairment of the coronary circulation in the acute period of cerebral stroke was shown to correlate with a subsequent course of CHD.