RESUMO
Examination of 42 liquidators of Chernobyl power station accident consequences, which was conducted in 5-6 years after the work in Chernobyl, proved 66.7% of examinees to have hypervolemia of hepatic circulation. These changes are due to hyperkinetic type of central hemodynamics. The data obtained prove absence of sclerotic lesions in liver.
Assuntos
Circulação Hepática , Centrais Elétricas , Liberação Nociva de Radioativos , Adulto , Volume Sanguíneo , Seguimentos , Humanos , Hepatopatias/diagnóstico , Hepatopatias/etiologia , Masculino , Pessoa de Meia-Idade , Lesões por Radiação/diagnóstico , Lesões por Radiação/etiologia , UcrâniaRESUMO
The comparative clinicopharmacological studies established the ability of hepatotropic agents with the membrane stabilizing properties and metabolic activity--trophopar, aika-phosphate and essential to stimulate to various degrees the processes of microsomal oxidation of antipyrine in hepatocytes at their insufficiency in patients with lesions of the hepatobiliary system of the alcohol and viral etiology. The studied drugs improve also the condition of the intrahepatic hemodynamics according to the findings of rheohepatography. The correlations between the positive dynamics of the values of antipyrine clearance, the degree of arterial blood filling (the rheographic index) and the increase of serum albumin content were found that confirms the ability of trophopar, aika-phosphate and essential to exert the complex influence on the systems and mechanisms of the realization of the liver antitoxic function.