1.
Org Lett
; 14(13): 3446-9, 2012 Jul 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22731678
RESUMO
The solid-phase synthesis of γ-AApeptides using a novel submonomeric approach that utilizes an allyl protection is reported. The strategy successfully circumvents the necessity of preparing γ-AApeptide building blocks in order to prepare γ-AApeptide sequences. This method will maximize the potential of developing chemically diverse γ-AApeptide libraries and thereby facilitate the biological applications of γ-AApeptides in the future.