An electrochemical aptasensor for detection of carbofuran using gold nanoparticles decorated hierarchical porous carbon as an effective sensing platform.

In this study, a novel electrochemical aptasensor for carbofuran (CBF) detection is prepared by gold nanoparticles decorated hierarchical porous carbon (Au@HPC). The prepared carbon materials show a three-dimensional hierarchical structure with a large specific surface area and a highly developed porous structure. Aptamers loading significantly improves when gold nanoparticles are embedded into the hierarchical porous carbon skeleton. Besides, Au@HPC modified electrode exhibits a large electroactive area and excellent electrochemical conductivity, serving as a promising platform for highly sensitive and selective electrochemical detection of CBF. The developed CBF electrochemical aptasensor shows a wide linear from 1.0 to 100000 pg/L with a detection limit of 0.5 pg/L, demonstrating an extraordinary sensitivity compared to other sensors for CBF detection. Additionally, the designed aptasensor was used to monitor the CBF in vegetable samples, with a recovery range from 98.4% to 104.8%. The results coincide with the standard test method, revealing its practicability in the food safety analysis.

A novel electrochemical aptasensor based on polyaniline and gold nanoparticles for ultrasensitive and selective detection of ascorbic acid.

Ascorbic acid (AA) is involved in many physiological activities of the body and plays an important role in maintaining and promoting human health. It is also present in many natural and artificial foods. Therefore, the development of highly sensitive and accurate AA sensors is highly desirable for human health monitoring, as well as other commercial application fields. Herein, an ultrasensitive and selective electrochemical sensor based on an aptamer was developed for the determination of AA for the first time. The aptasensor was fabricated by modifying a composite made of polyaniline (PANI) and gold nanoparticles (AuNPs) on a glassy carbon electrode. The morphologies and electrochemical properties of the resulting electrodes were characterized by various analytical methods. The results indicated relatively good electrical conduction properties of PANI for accelerated electron transfer. The modification with AuNPs provided signal amplification, suitable for applications as novel platforms for the sensitive sensing of AA. Under optimized conditions, the proposed aptasensor displayed a wide linear response toward the detection of AA from 1.0 to 1.0 × 105 ng L-1 coupled with a low detection limit of 0.10 ng L-1. The sensor also exhibited excellent selectivity and high stability, with at least 2000-fold higher sensitivity than similar previously reported methods. Importantly, the aptasensor exhibited promising properties for the determination of AA in real fruits, vegetables, and infant milk powder, thereby showing potential for food analysis.

Highly sensitive electrochemical detection of myricetin in food samples based on the enhancement effect of Al-MOFs.

Microporous aluminum-based metal-organic frameworks (CAU-1) are used to develop a simple and sensitive electrochemical sensor for myricetin (MYR) based on a modified carbon paste electrode (CPE) for the first time. The morphologies and electrochemical properties of the as-synthesized CAU-1 are studied utilizing various analytical methods including scanning electron microscopy, transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, N2 adsorption-desorption, and electrochemical impedance spectroscopy. In terms of electrochemical oxidation of MYR, CAU-1/CPE with its large number of active micropores and rapid electron transfer demonstrates superior performance compared to the bare CPE. Under optimized conditions, the calibration curve for MYR exhibits a linear range of 1.0-10 µg L-1 and 10-1000 µg L-1 with a detection limit of 0.50 µg L-1. The developed CAU-1/CPE exhibits superior analytical characteristics, compared to previously reported electrochemical sensors for MYR detection. Furthermore, CAU-1/CPE is employed to determine MYR in Myrica bark samples, and the results are consistent with those obtained by high-performance liquid chromatography, demonstrating the excellent potential of CAU-1/CPE for the rapid analysis of MYR in complicated real samples.