[A protein specific to bovine amniotic fluid]. / Belok, spetsificheskii dlia amnioticheskoi zhidkosti korov.

It is shown that in case of a secretory action of amnion, a specific protein characterized by an immunostimulating action is brought to the amniotic liquid. Its participation in the embryogenesis processes is assumed.

[Isolation and characteristics of immune complexes circulating in the serum of acute leukemia patients]. / Vydelenie i kharakteristika immunnykh kompleksov, tsirkuliruiushchikh v syvorotke krovi bol'nykh ostrym leikozom.

Immunoglobulin G-containing immune complexes are obtained from blood serum of patients with acute leukemia by the method which includes precipitation using polyethylene glycol-6000, Sephadex G-200 gel filtration and protein A-sepharose affinity chromatography (pH 8.5). Immunologically active antibodies and antigens of complexes are isolated by Sephadex G-200 gel chromatography under conditions of dissociation (the sodium-citrate buffer, pH 7.5, 9 M urea). The immune complexes with the antigens and antibodies isolated from them are partially characterized using disc-immunoelectrophoresis, isoelectrofocusing and immune-isoelectrofocusing.

[Potentiometric studies of ionogenic groups of immunoglobulin G characteristic of malignant growth]. / Potentsiometricheskoe issledovanie ionogennykh grupp immunoglobulina G, kharakternogo dlia zlokachestvennogo rosta.

Application of the method of potentiometric acid-base titration for studying the character of available for titration ionogenic groups of immunoglobulin G characteristic of malignant growth and immunoglobulin G isolated from the health people blood serum made it possible to detect some differences evidencing for different conformation of the molecules of the proteins under study.

[Characteristics of the serum proteins of cancer patients in an acid medium]. / Osoblyvosti bilkiv syrovatky krovi khvorykh na rak u kyslomu seredovyshchi

Under condition of nitric acid titration of aqueous and hydrochloride solutions of sera from patients with cancer certain serum proteins become insoluble at higher values of pH as compared to the other proteins of sera. The latter lose solubility at the pH values corresponding to transition to the insoluble state of serum proteins from people without malignant tumours. The results of studies in the temperature regime effect on the found peculiarities of serum proteins from patients with cancer in the acid medium permit assuming that the physical bases of the marked transitions are different. The mentioned regularity is not pronounced with a temperature rise up to 35--40 degree C.