Utilizing Ant Forest technology to foster sustainable behaviors: A novel approach towards environmental conservation.

Amidst mounting environmental threats and exacerbated global risks from climate change, the urgency for sustainable behaviors has never been more critical, demanding concerted efforts to cultivate individual actions for environmental conservation. Ant Forest technology, a groundbreaking innovation for sustainable lifestyles, stands at the forefront of this battle, harnessing technological advancements to drive positive environmental impact and must be championed. This research investigates the dynamics of environmental conservation behaviors facilitated by Ant Forest Technology. Employing a theoretical framework integrating the Technology Acceptance Model (TAM) and Self-Determination Theory (SDT), the study explores the impact of autonomous and controlled motivation on attitudes, intentions, and conservation behaviors. Furthermore, the research assesses the influence of knowledge disseminated through Ant Forest Technology on users' intentions and behavior toward conservation behaviors. The study utilized the partial least square structural equation modeling in its analysis. Findings reveal that both motivational factors and knowledge significantly shape users' engagement in conservation behaviors activities through perceived ease of use and usefulness. These insights contribute to the development of effective policies and interventions aimed at harnessing Ant Forest Technology as a powerful tool for fostering widespread environmental conservation behaviors.

Households' food waste behavior prediction from a moral perspective: a case of China.

The increasing rate of food waste is becoming a threat to realizing Sustainable Development goal 2 by 2030. A significant portion of food is wasted along the entire food supply chain, resulting in adverse economic, ecological and social consequences. Inferring from the norm activation model (NAM), the study investigates the influence of benefits awareness, lack of concern and personal norm on households' food waste reduction intention. Gathering research data via an online survey in Jiangsu province in China, a total sample of 408 responses were analyzed using structural equation model. It was found that the extended NAM model developed is more appropriate for assessing food waste reduction intention with a significant improved explanatory potential from 32.0 to 52.0%. Households' awareness of consequences was established to have a positive effect on ascription of responsibility, and they both impact personal norm positively. Personal norm influences food waste reduction intention positively. Again, the awareness of the benefits for reducing food waste affects households' intention to reduce food waste positively. Lack of concern for food waste negatively affects their personal norm and food waste reduction intentions. These findings furnish valuable insights for future campaigns to educate people and influence their moral norms toward the importance and involvement in achieving Sustainable Development Goals related to food waste.

Curbing vehicular urban pollution in China: Investigating the usage intentionof public electric buses.

Public electric bus (PEB) usage remains critical in reducing carbon emissions, traffic congestion, energy consumption, resource exhaustion, and environmental pollution. PEB usage revolves around consumer acceptance, and assessing the psychological factors accounting for using PEBs is essential in mitigating these challenges for a sustainable environment. The study extends the reasoned action theory (TRA) with environmental awareness, convenience, and personal norms in investigating residents' intention to use electric buses in Nanjing, China. 405 responses were gathered through an online survey and evaluated using Structural Equation Modeling (SEM). Statistical analysis showed that the structural model (66.4%) explained public electric bus use better than the original TRA model (20.7%). Attitude, subjective norms, personal norms, environmental awareness, and convenience directly influenced the intention to use PEBs. Personal norms related to attitude positively. Environmental awareness related to personal norms in PEB use. Subjective norms partially mediated the impact of personal norms on the intention to use PEBs. Convenience moderated the interaction between personal norms and intention to use PEBs. Respondents differed in income level, educational level, and employment but not gender in their inclinations to use PEBs. The current study recommends potent policy implications to enhance and ensure the maximum use of PEBs.

Does domestic investment matter? A multivariate time series analysis of the energy-CO2 emission-growth nexus in Ghana.

The economic cost of greenhouse gas (GHG) emissions to African economies have increased. Therefore, GHG emissions and their concomitant effect on the environment are fast becoming costly for emerging economies like Ghana. Hence, the justification for the growing literature on the subject. This study employed the Autoregressive Distributive Lag (ARDL) bounds test and Granger causality techniques with data from 1983 to 2014. The study examines the dynamic relationship between income growth, power consumption, and carbon dioxide (CO2) emissions in Ghana, capturing the role of domestic investment and foreign direct investment (FDI) in the nexus. All variables were found to be cointegrated in the long run based on the bounds test. The Granger causality test indicates a unidirectional causality from energy consumption to CO2 emissions and economic growth. Furthermore, a unidirectional causality from CO2 to economic growth was found in Ghana. Results from the error correction model and the bounds tests indicate that, while energy consumption increases carbon emissions by more than 44%, the lagged values of domestic investment were found to reduce CO2 emissions by more than 41% in both the short run and the long run. Due to the significant effect of domestic investments on the reduction of CO2 emissions, the study recommends policymakers to adopt policies that may increase domestic capital in place of FDI, which has been proven to exacerbate environmental degradation in host countries.

Sustainable development of West African economies to achieve environmental quality.

The deterioration of environmental quality spurred on by rising greenhouse gas (GHG) emissions is the main threat to reducing carbon footprint. Africa has recently been identified as having experienced excessive temperatures above pre-industrial standards. Despite its lower GHG emissions, Africa continues to be among the most impacted areas of the world by global warming. However, this research scrutinizes the effect of human capital and trade openness on the ecological footprint (ECF) and carbon dioxide (CO2) emissions using data from West Africa from 1995 to 2016. The research used dynamic ordinary least squares, fully modified ordinary least squares, and paired Dumitrescu-Hurlin panel causality tests for its assessment. The study's findings are as follows: (1) The study found that human capital and trade openness decrease the ecological footprint in West Africa; (2) globalization reduces CO2 emissions while also increasing the ecological footprint; (3) the analysis reveals that natural resources and the population improve environmental quality in West Africa, while biocapacity reduces the ecological footprint and improves CO2 emissions in the region; and (4) the study revealed the bidirectional causality between biocapacity, the population, and ECF. The study also revealed the bidirectional causality between biocapacity, population, human capital, natural resources, and CO2 emissions, while ecological footprint is unidirectionally causally related to globalization, human capital, and trade capital. Unidirectional causality runs from the ecological footprint, globalization, and trade openness to CO2 emissions. To ensure their countries have a long-term future, policymakers in West Africa should take action to limit overexploitation of natural resources and encourage people to live more sustainably. The study suggested that West African countries adopt "green growth" policies and improve technology to help their economies and the environment.

Renewable energy demand, financial reforms, and environmental quality in West Africa.

Sustainable Development Goal (SDG-7) stipulates the need for clean energy, reduced carbon dioxide emissions, prevention of environmental degradation, promotion of biodiversity, and ecosystem preservation. Toward achieving these goals, this study provides new evidence on the causal link between renewable energy demand, financial reforms, economic growth, foreign direct investment, and environmental quality among emerging West African economies. The study adopted the fully modified ordinary least squares, dynamic ordinary least squares, pooled mean group estimation, and Granger causality test for its analysis. It was found that renewable energy demand has been favorable to the environmental health of West African economies. Also, financial reforms made within the region contributed to increasing the ecological footprints of the region. Direct investments from foreigners showed encouraging results as they improved the quality of the environment. We also found a unidirectional causality from ecological footprints to renewable energy demand and financial reforms but a bidirectional relationship with economic growth and foreign direct investment. Moreover, it was evident that ecological footprints Granger cause financial reforms and economic growth but not vice versa. Policy recommendations outlined encourage governments and policymakers to embark on intensive clean energy technologies and effective green financial reforms to help achieve Sustainable Development Goals.

The potential energy and environmental benefits of global recyclable resources.

Globally, the production of vast volumes of municipal solid waste impacts public health and the climate. Greening the solid waste sector could contribute to the achievement of the Sustainable Development Goals (SDGs). Therefore, this study assessed how the potential electricity and environmental benefits of recycling paper and plastic wastes could contribute to the achievement of the SDGs. The study used model equations methods to estimate the electricity consumption, diesel consumption, and greenhouse gas (GHG) emissions saved due to recycling. The key findings show that the 132.4 thousand toe/day of electricity saved globally in 2012 soared to 182.3 thousand toe/day in 2025. In 2012 and 2025, an average of 63.6% of electricity was saved. Globally, recycling saved a record of 1.4 million ktons CO2eq/day of GHG emissions in 2012 and 1.9 million ktons CO2eq/day in 2025. It was further realized that the overall volume of diesel fuel saved in 2012 grew from 511,146 to 703,887 million Liters/day in 2025, representing a rise of 37.7%. The sensitivity analysis shows an increase in the waste collection rate, the fraction of paper waste, the fraction of plastic waste, and the recycling rate in 2025 will boost recyclable resources' energy and environmental benefits. The findings of this study could offer scientific guidance for the achievement of the SDGs related to solid waste recycling and management.

Usefulness of Achieving ≥10 METs With a Negative Stress Electrocardiogram to Screen for High-Risk Obstructive Coronary Artery Disease in Patients Referred for Coronary Angiography After Exercise Stress Testing.

Functional capacity in exercise stress testing is an independent predictor of cardiac events. Routine use of nuclear perfusion imaging increases radiation burden and cost. Our goal was to assess the clinical utility of exercise functional capacity with stress electrocardiogram (ECG) as an adjunct in predicting the presence of high-risk obstructive coronary artery disease (CAD) on diagnostic coronary angiography. We performed a retrospective study of patients who underwent exercise stress testing for the evaluation of chest pain and underwent diagnostic coronary angiography within the subsequent 3 months. High-risk CAD was defined as coronary artery diameter stenosis of ≥70% in the proximal left anterior descending artery, ≥70% diameter stenosis in 3 major epicardial arteries, or ≥50% diameter stenosis in the left main artery. Univariable and multivariable analyses were performed to identify predictors of high-risk CAD. Of the 412 patients, 105 (25%) had high-risk CAD on coronary angiography. On multivariate logistic regression, we found that positive stress ECG, abnormal stress imaging, left ventricular ejection fraction, and male gender were independent predictors of high-risk CAD. The strongest predictor was positive stress ECG (hazard ratio 3.16, 95% confidence interval 1.90 to 5.27, p <0.001). Functional capacity measures alone were not independent predictors of high-risk CAD. Achieving ≥10 METs with a negative stress ECG resulted in 94% sensitivity and 97% negative predictive value in identifying high-risk CAD. This supports the strategy for provisional use of myocardial perfusion imaging in patients with low functional capacity and/or abnormal stress ECG to minimize cost and radiation exposure.

Extracellular loop C of NPC1L1 is important for binding to ezetimibe.

Niemann-Pick C1-like protein (NPC1L1) mediates the absorption of dietary cholesterol in the proximal region of the intestine, a process that is blocked by cholesterol absorption inhibitors (CAIs), including ezetimibe (EZE). Using a proteomic approach, we demonstrate that NPC1L1 is the protein to which EZE and its analogs bind. Next, we determined the site of interaction of EZE analogs with NPC1L1 by exploiting the different binding affinities of mouse and dog NPC1L1 for the radioligand analog of EZE, [(3)H]AS. Chimeric and mutational studies indicate that high-affinity binding of [(3)H]AS to dog NPC1L1 depends on molecular determinants present in a 61-aa region of a large extracellular domain (loop C), where Phe-532 and Met-543 appear to be key contributors. These data suggest that the [(3)H]AS-binding site resides in the intestinal lumen and are consistent with preclinical data demonstrating in vivo efficacy of a minimally bioavailable CAI. Furthermore, these determinants of [(3)H]AS binding lie immediately adjacent to a hotspot of human NPC1L1 polymorphisms correlated with hypoabsorption of cholesterol. These observations, taken together with the recently described binding of cholesterol to the N terminus (loop A) of the close NPC1L1 homologue, NPC1, may provide a molecular basis for understanding EZE inhibition of NPC1L1-mediated cholesterol absorption. Specifically, EZE binding to an extracellular site distinct from where cholesterol binds prevents conformational changes in NPC1L1 that are necessary for the translocation of cholesterol across the membrane.

Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

Absorption of dietary cholesterol in the proximal region of the intestine is mediated by Niemann-Pick C1-like protein (NPC1L1) and is sensitive to the cholesterol absorption inhibitor ezetimibe (EZE). Although a correlation exists between EZE binding to NPC1L1 in vitro and efficacy in vivo, the precise nature of interaction(s) between NPC1L1, EZE, and cholesterol remain unclear. Here, we analyze the direct relationship between EZE analog binding to NPC1L1 and its influence on cholesterol influx in a novel in vitro system. Using the EZE analog [(3)H]AS, an assay that quantitatively measures the expression of NPC1L1 on the cell surface has been developed. It is noteworthy that whereas two cell lines (CaCo-2 and HepG2) commonly used for studying NPC1L1-dependent processes express almost undetectable levels of NPC1L1 at the cell surface, polarized Madin-Darby canine kidney (MDCKII) cells endogenously express 4 x 10(5) [(3)H]AS sites/cell under basal conditions. Depleting endogenous cholesterol with the HMG CoA reductase inhibitor lovastatin leads to a 2-fold increase in the surface expression of NPC1L1, supporting the contention that MDCKII cells respond to changes in cholesterol homeostasis by up-regulating a pathway for cholesterol influx. However, a significant increase in surface expression levels of NPC1L1 is necessary to characterize a pharmacologically sensitive, EZE-dependent pathway of cholesterol uptake in these cells. Remarkably, the affinity of EZE analogs for binding to NPC1L1 is almost identical to the IC(50) blocking cholesterol flux through NPC1L1 in MDCKII cells. From a mechanistic standpoint, these observations support the contention that EZE analogs and cholesterol share the same/overlapping binding site(s) or are tightly coupled through allosteric interactions.