[Enhancement of the effect of radiotherapy of Guerin's carcinoma by tinidazole]. / Usilenie luchevogo vozdeistviia na kartsinomu Gerena s pomoshch'iu tinidazola.

Tinidazol, an electron-acceptor compound, was studied for its influence on the effectiveness of radiation treatment of Guerin's carcinoma. It was shown in terms of tumour regression, percentage of inhibition, time of tumour volume doubling, rate of the tumour growth renewal and average survival that in the presence of tinidazol, the antitumour effectiveness of radiation treatment is 1.6-2.0 times as high as radiation alone. Morphologic studies confirm the ability of tinidazol to enhance the radiation damage.