[Use of dermatography as treatment method in various medical specialties]. / Anwendung von Dermatographie als Behandlungsmethode in verschiedenen medizinischen Fachbereichen.

Dermatography is the application of tattooing techniques in medicine. In the past, several techniques were tried but none led to reproducible results. Dermatography has been improved over the last ten years, providing techniques which are both generally applicable and reproducible. It is a suitable treatment modality for permanently camouflaging disturbing discolorations and scars. This paper covers technical and medical aspects of dermatography, as well the indications.

[Oral cancer. The importance of early diagnosis and role of the dentist]. / Cancer buccal. L'importance du diagnostic précoce et le rôle du dentiste.

Early diagnosis is an significantly relevant factor in the prognosis of oral cavity carcinomas. Knowledge of the clinical and oral manifestations of pre-cancerous lesions in general dentistry is of paramount importance. The initial treatment, follow-up schedule and reference timing are given in a decision chart. Special attention is given to the timing of biopsies in the treatment plan.

[Fractures of the extremely atrophic mandible]. / Fracturen van de extreem atrofische onderkaak.

Fracture treatment of the extremely atrophic mandible is a challenge to the surgeon because of the special problems and complications. A reliable method is the internal fixation technique with multiple split rib grafts. By use of immediate split rib bone grafting secondary revisions and reconstructions may be avoided. The technique and rationale are discussed.

Relationship between cell kinetics and radiation-induced arrest of proliferating cells in G2: relevance to efficacy of radiotherapy.

Monitoring the radiation-induced G2-arrest with flow cytometry disclosed the relationship between the pattern of accumulation in G2 and the cell kinetics (Tc), as assessed with semi-continuous labelling. A close relationship between these two parameters was observed in a murine mammary tumour after high dose-rate irradiation and in human cervix tumours (xenografted and in patients) after low dose-rate irradiation. In inoperable tumours of the oral cavity, a G2-arrest, observed in the first two weeks of fractionated therapy, was found to predict a local cure. Consequently, it was concluded that the cells accumulated in G2 were not doomed cells. This process of radiation-induced synchronization might be exploited in fractionation schemes of which treatment intervals are adjusted to the Tc-related timing of the radiation-induced G2-arrest.

Utilization of the pedicle of the temporal-forehead-flap to close defects in the maxilla after tumour surgery.

The forehead flap can be used to close defects in the cheek and floor of the mouth, its pedicle can be used to close defects in the maxilla. This method was successfully applied in six patients.

Primitive neuroectodermal tumour of the maxilla. Light microscopy and ultrastructural observations.

Primitive neuroectodermal tumour is a rarely encountered lesion, mainly occurring within the central nervous system. A case is reported in which the tumour was situated in the anterior maxilla. Light microscopy and ultrastructural features that made it possible to differentiate the lesion from other small round-cell tumours are discussed. Combined surgical and radiotherapeutic intervention proved to be successful in eradicating the neoplasm.