RESUMO
Lymphocytic hypophysitis (LH) is a neuroendocrine disorder characterised by autoimmune inflammation of the pituitary gland with resultant pituitary dysfunction. Rarely, the presenting symptom can be diplopia due to irritation of the third, fourth, or sixth cranial nerves secondary to cavernous sinus involvement of the mass or increased intracranial pressure. We describe the case of a healthy, 20-year-old female with a pupillary sparing third nerve palsy, who was subsequently diagnosed with LH after an endoscopic transsphenoidal biopsy of the mass. She was treated with hormone replacement therapy and corticosteroids, resulting in full resolution of symptoms with no recurrence to date. To our knowledge, this is the first report of a third nerve palsy due to definitive biopsy proven LH. Despite its rarity, the unique presentation and favourable evolution of this case should aid clinicians in its timely recognition, appropriate workup, and treatment.
RESUMO
PURPOSE: To present a case study that describes novel ocular manifestations of Powassan virus encephalitis using fundus imaging. STUDY DESIGN: Case Report. RESULTS: In this case study, fundus photographs, fundus autofluorescence, and fluorescein angiography were used to highlight Powassan virus-induced multifocal choroiditis with linear streaks. CONCLUSIONS: Our case study demonstrates novel retinal findings of Powassan virus, a pattern which is commonly described in eyes infected with West Nile Virus, another type of flavivirus.
