RESUMO
There have been established opposite reactions in the cardiovascular system during formation of dust-induced pathology of lungs: a common finding in patients with pneumoconiosis is alterations in the left heart, while in chronic dust bronchitis the same is true of the right heart. In the authors' opinion, different states of pulmonary surfactant in the above conditions account for this observation. Inhibition of synthesis of the pulmonary surfactant associated with the development of the blood and tissue phospholipid deficiency makes for the evolution of atherosclerosis in patients with pneumoconiosis while enhancement of the phospholipid production by the lungs accompanied by elevation of their blood content is an important factor inhibiting the processes of atherogenesis in patients with dust bronchitis.
Assuntos
Antracossilicose/complicações , Arteriosclerose/etiologia , Bronquite/complicações , Surfactantes Pulmonares/análise , Adulto , Antracossilicose/metabolismo , Arteriosclerose/metabolismo , Bronquite/metabolismo , Líquido da Lavagem Broncoalveolar/química , Doença Crônica , Minas de Carvão , Humanos , Lipídeos/análise , Pessoa de Meia-Idade , UcrâniaRESUMO
The authors analyzed morbidity and invalidity in miners engaged in liquidation of Chernobyl disaster sequels depending on the duration of stay in increased radiation background, radiation dose, length of work in the mines. Among the nosological entities prevailed vegeto-vascular dystonia, thyroid and gastrointestinal pathology.
Assuntos
Acidentes de Trabalho , Avaliação da Deficiência , Mineração , Reatores Nucleares , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Centrais Elétricas , Poluentes Radioativos/efeitos adversos , Acidentes de Trabalho/estatística & dados numéricos , Adulto , Distribuição por Idade , Humanos , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional/estatística & dados numéricos , Fatores de Tempo , Ucrânia/epidemiologiaRESUMO
AIM OF THE STUDY: establishing a relationship between the condition of the pulmonary surfactant and external respiration function in Donbass coal miners with initial and advanced forms of dust-induced lung pathology. One of the early manifestations of lung pathology in miners is increased synthesis and secretion of the surfactant on the alveolar surface with disorders of its functional activity evidencing disorders of lipid excretion from the pulmonary tissue. The presence of albumin in the expired air indicates the presence of alternative processes in the bronchopulmonary apparatus, and highest albumin content in patients with pneumoconiosis and chronic dust-induced bronchitis may be an index of activity of the inflammatory process.
Assuntos
Minas de Carvão , Pneumoconiose/etiologia , Surfactantes Pulmonares/análise , Testes Respiratórios , Bronquite/diagnóstico , Bronquite/etiologia , Doença Crônica , Humanos , Pulmão/diagnóstico por imagem , Pneumoconiose/diagnóstico , Radiografia , Testes de Função Respiratória , UcrâniaRESUMO
Pulsimetry proved to be the most acceptable method for estimating energy requirements of miners working under extreme conditions with constantly changing ergometric parameters. It has been established that the mean daily energy requirements of miners working in deep coal mines under conditions of high temperature comprise 3500 kcal. Energy requirements for the main types of the physical activity of workers in deep mines have been calculated, basing on basal metabolism, metabolic constants for varying activities have been determined.
Assuntos
Minas de Carvão/normas , Metabolismo Energético/fisiologia , Fenômenos Fisiológicos da Nutrição/fisiologia , Medicina do Trabalho/métodos , Esforço Físico/fisiologia , Pulso Arterial/fisiologia , Ingestão de Energia/fisiologia , Testes de Função Cardíaca/métodos , Humanos , Necessidades Nutricionais , Medicina do Trabalho/normas , UcrâniaRESUMO
To determine the frequency and characteristics of bacterial discharge, a cultural investigation of 166 patients' sputa was performed in three groups: Group 1: 37 pneumoconiosis at 2nd and 3d stages and active TB cases; Group 2: 41 non-active TB cases; Group 3: 88 cases of pneumoconiosis without concomitant TB infection. The sputa were studied with bacteriological techniques to determine the biologically changed forms of MBT. As a whole, the L-forms were found in 66.3% cases: Group 1-97.3%, Group 2-56.1%, Group 3-57.9% cases. In Group 2 and 3, the L-form bacterial discharge was scarce, predominantly with small monomorphic vacuolized forms.