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1.
Harv Rev Psychiatry ; 31(4): 195-201, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37437251

RESUMO

ABSTRACT: The synergistic epidemics of COVID-19, racial injustice, and health inequities sparked an unprecedented commitment from US hospital systems and treatment settings to address health disparities by increasing access to care for historically oppressed and underserved communities. However, the inability of hospital systems to actually provide multiculturally responsive care and, more broadly, to consistently practice cultural humility will only exacerbate patient distrust and the deleterious health and social outcomes we seek to mitigate. This perspective article describes the development of a multidisciplinary team of mental health providers committed to delivering culturally responsive mental health treatment while promoting inclusive workplace environments. We outline the Multicultural Psychology Consultation Team's (MPCT) origin, design, process, and structure and discuss successes and challenges in maintaining the model in its first two years. We recommend that systemic infusion of cultural humility, multiculturally responsive clinical care, and support for providers delivering care be prioritized in concert with efforts to increase access to care for diverse patients. We offer MPCT as a model for supporting these aims.


Assuntos
COVID-19 , Humanos , Centros Médicos Acadêmicos , Saúde Mental , Psicoterapia , Encaminhamento e Consulta
2.
Artigo em Inglês | MEDLINE | ID: mdl-37521712

RESUMO

Many individuals with obsessive-compulsive disorder (OCD) report sensory-based urges (e.g. 'not-just-right experiences') in addition to, or instead of, concrete fear-based obsessions. These sensations may be comparable to normative "urges-for-action" (UFA), such as the urge to blink. While research has identified altered functioning of brain regions related to UFA in OCD, little is known about behavioral patterns of urge suppression in the disorder. Using an urge-to-blink task as a model for sensory-based urges, this study compared failures of urge suppression between OCD patients and controls by measuring eyeblinks during 60-second blocks of instructed blink suppression. Cox shared frailty models estimated the hazard of first blinks during each 60-second block and recurrent blinks following each initial erroneous blink. OCD patients demonstrated a higher hazard of first and recurrent blinks compared to controls, suggesting greater difficulty resisting repetitive sensory-based urges. Within OCD, relationships between task outcomes and symptom severity were inconsistent. Findings provide support for a deficit in delaying initial urge-induced actions and terminating subsequent actions in OCD, which is not clearly related to clinical heterogeneity. Elucidating the nature of behavioral resistance to urges is relevant for informing conceptualizations of obsessive-compulsive psychopathology and optimizing treatment outcomes.

3.
Behav Ther ; 52(5): 1277-1285, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34452679

RESUMO

Exposure and ritual prevention (ERP) and pharmacotherapy are typically associated with significant symptom reductions for individuals with obsessive-compulsive disorder (OCD). However, many patients are left with residual symptoms and other patients do not respond. There is increasing evidence that delays in sleep timing/circadian rhythms are associated with OCD but the potential effects of delays in sleep timing on ERP warrant attention. This paper presents data from 31 outpatients with OCD who participated in ERP. Results showed that delayed sleep timing was common and that individuals with delayed bedtimes benefited significantly less from treatment and were significantly more likely to be nonresponders compared to individuals with earlier bedtimes. Further, the effects of sleep timing remained statistically significant even after controlling for global sleep quality, negative affect, and several other variables. These findings add to a growing literature suggesting the utility of better understanding the role of disruptions in the timing of sleep in OCD.


Assuntos
Transtorno Obsessivo-Compulsivo , Transtornos do Sono-Vigília , Comportamento Ritualístico , Comportamento Compulsivo , Humanos , Sono , Resultado do Tratamento
4.
Front Psychol ; 11: 572153, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33192865

RESUMO

Alongside concern about the physical health impacts of the coronavirus disease 2019 (COVID-19) crisis, public health officials have also raised concerns about the potential for massive mental health impact. This has led many to wonder, how are individuals with obsessive-compulsive disorder (OCD), and especially those with contamination fears, doing in the era of COVID-19? We present data from eight patients in our residential treatment program for OCD who were admitted prior to any COVID-19 restrictions and continued in treatment at the facility during the pandemic. Much like the general population, our patients varied in the ways they were impacted by COVID-19, yet the majority experienced improvements in OCD symptoms despite the context. This is not to downplay the many ways in which our patients were personally affected by COVID-19. Rather our patients' relatively resilient responses mirror our program's treatment model, which emphasizes exposure and response prevention (ERP) within the complementary framework of acceptance and commitment therapy (ACT). The intention of this article is to challenge the notion that by definition this population will fare worse than the general public or that ERP cannot proceed effectively during this time. In contrast, we underscore that effective OCD treatment can and should continue in the era of COVID-19.

5.
J Consult Clin Psychol ; 88(11): 971-982, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33136421

RESUMO

OBJECTIVE: Bidirectional relations between sleep disturbances, depression symptoms, and anxiety symptoms have been frequently observed in empirical studies; however, little is known about the temporal relations between these variables in the context of treatment. METHOD: The current study examines the temporal relations between sleep parameters, depression symptoms, and anxiety symptoms in a large sample of individuals undergoing intensive cognitive-behavioral partial hospital treatment (N = 1,184). Random-intercept cross-lagged panel models were fit to these data to determine whether (1) sleep parameters uniquely predicted subsequent depression and anxiety symptoms and (2) depression and anxiety symptoms uniquely predicted subsequent sleep parameters. RESULTS: Results revealed relations in both directions: later than usual bedtimes predicted higher than usual anxiety and depression the next day, shorter than usual sleep duration predicted higher than usual depression the next day, shorter than usual nighttime sleep onset latency predicted higher than usual anxiety the next day, and higher than usual anxiety predicted shorter than usual sleep duration on the next night. CONCLUSIONS: These finding suggest the potential value of examining sleep behaviors associated with sleep timing and circadian rhythms as important transdiagnostic factors during treatment for anxiety and depression. We discuss the implications for future studies of the relations between sleep and psychopathology symptoms and understanding individuals' experiences in the context of cognitive-behavioral treatment. (PsycInfo Database Record (c) 2020 APA, all rights reserved).


Assuntos
Ansiedade/psicologia , Terapia Cognitivo-Comportamental , Depressão/psicologia , Privação do Sono/psicologia , Adulto , Ritmo Circadiano , Correlação de Dados , Feminino , Humanos , Masculino , Modelos Psicológicos
6.
Behav Ther ; 51(4): 559-571, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32586430

RESUMO

Delays in behavioral and biological circadian rhythms (e.g., sleep timing, melatonin secretion) are found more frequently in individuals with severe and treatment-resistant obsessive-compulsive disorder (OCD). In recent years, it has been documented that these delays in behavioral and biological circadian rhythms are associated with more severe OCD symptoms and poorer response to some OCD treatments. This study examined self-reported sleep behaviors in individuals taking part in an intensive treatment for OCD and the relations between these and OCD symptoms (both at admission to and discharge from the treatment program). Replicating previous findings in less severe populations, delayed sleep phases were relatively common in this group and later bedtimes were associated with more severe OCD symptoms at admission. Sleep onset latency and sleep duration were not associated with OCD symptom severity at admission. Later bedtimes were not associated with self-reported depression or worry symptom severity. There was no evidence of sleep behaviors affecting change in OCD symptoms from admission to discharge from treatment-however, later bedtimes at admission were associated with more severe OCD symptoms at admission and discharge from treatment. There was no evidence of sleep onset latency or sleep duration having a similar predictive effect. More severe OCD symptoms at admission were also associated with later bedtimes at admission and discharge from treatment. These bidirectional predictive relations between late bedtimes and OCD symptoms were of small effect size but support the potential value of evaluating sleep timing in individuals with severe and/or treatment-resistant OCD.


Assuntos
Transtorno Obsessivo-Compulsivo , Humanos , Transtorno Obsessivo-Compulsivo/terapia , Tratamento Domiciliar , Sono , Transtornos do Sono-Vigília
7.
Psychiatry Res ; 273: 788-797, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-31207867

RESUMO

Depression, anxiety, sleep disturbances and poor relationship functioning often co-occur with the confluence of these factors contributing to greater suicide risk. This study investigated whether the pathways between depression, anxiety, sleep disturbances, and relationship functioning differentiated patients with suicide attempt history from those with suicidal ideation history. Patients seeking partial hospital treatment for severe psychiatric symptoms (N = 180) completed interviews assessing psychiatric and suicidal symptom histories, and self-report measures of sleep behaviors, anxiety, depression, and relationship functioning. Multiple sleep behaviors were examined: duration, sleep onset latency, and bedtime. Bias-corrected bootstrap mediation and moderated mediation analyses with suicide attempt as the moderator were used to evaluate pathways between variables. Among patients with ideation and attempt history, (1) sleep onset latency significantly mediated the association between depression and relationship functioning and that between anxiety and relationship functioning; (2) relationship functioning significantly mediated the association between depression and sleep onset latency and that between anxiety and sleep onset latency. These pathways were not significant among patients with suicidal ideation only. No other sleep behaviors were related to study variables. The reciprocal relationship between disrupted sleep onset latency and poor relationship functioning was specifically linked to more severe psychiatric symptoms among acute patients with suicide attempt histories.


Assuntos
Afeto/fisiologia , Relações Interpessoais , Latência do Sono/fisiologia , Ideação Suicida , Tentativa de Suicídio/psicologia , Adulto , Ansiedade/diagnóstico , Ansiedade/fisiopatologia , Ansiedade/psicologia , Depressão/diagnóstico , Depressão/fisiopatologia , Depressão/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Autorrelato , Comportamento Autodestrutivo/diagnóstico , Comportamento Autodestrutivo/fisiopatologia , Comportamento Autodestrutivo/psicologia , Adulto Jovem
8.
Behav Ther ; 50(2): 300-313, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30824247

RESUMO

Understanding the role of patient motivation in OCD treatment is of clinical importance given the requisite autonomous role of patients in Exposure and Response Prevention. The present study investigated state- and trait-like relations between three variables: two previously established motivational constructs, readiness to change (RTC) and committed action (CA), derived from the University of Rhode Island Change Assessment, and OCD symptom severity as measured by the self-report Yale-Brown Obsessive Compulsive Scale (Y-BOCS-SR). Utilizing a random-intercept cross-lagged panel model (RI-CLPM) design, we assessed autoregressive, within-time correlations, and cross-lagged effects of RTC, CA, and Y-BOCS-SR scores at admission, month 1 of treatment, and discharge from an intensive/residential treatment program for OCD. Results revealed significant autoregressive (i.e., state-like) effects for CA and Y-BOCS-SR, negative within-time correlations between state CA and Y-BOCS-SR across all time points, a positive within-time correlation between state CA and RTC at admission, and a cross-lagged effect between state Y-BOCS-SR at month 1 of treatment and state RTC at discharge. Results also demonstrated that the stability of the RTC variable was attributable to trait-like factors in the present sample. This study is novel in its use of RI-CLPM in an OCD sample and represents an important addition to the literature on the longitudinal impacts of dynamic constructs of motivation. Our findings may provide future researchers with strategies to supplement ERP with CA-driven motivational interviewing.


Assuntos
Motivação , Transtorno Obsessivo-Compulsivo/diagnóstico , Transtorno Obsessivo-Compulsivo/psicologia , Índice de Gravidade de Doença , Adaptação Psicológica/fisiologia , Adulto , Feminino , Comportamentos Relacionados com a Saúde/fisiologia , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Motivação/fisiologia , Entrevista Motivacional/tendências , Transtorno Obsessivo-Compulsivo/terapia , Autorrelato
9.
J Affect Disord ; 245: 827-833, 2019 02 15.
Artigo em Inglês | MEDLINE | ID: mdl-30699866

RESUMO

BACKGROUND: This study investigated distinct trajectories of treatment response in a naturalistic intensive/residential treatment (IRT) program for adults with severe obsessive-compulsive disorder (OCD). We hypothesized that: (1) distinct trajectories would emerge and (2) demographic variables, psychiatric comorbidity, OCD symptom subtype, level of insight, previous exposure and response prevention (ERP) treatment, and quality of life, would differentially predict assignment to these trajectories. METHODS: Participants included 305 individuals with primary OCD admitted for IRT. RESULTS: Two trajectories emerged over the course of the first eight weeks of treatment, with the vast majority of participants demonstrating treatment response. The first trajectory (96%, n = 292) showed a negative, linear treatment response (a.k.a. "linear responders") and more severe OCD symptoms at admission. The second trajectory (4%, n = 13) had less severe OCD symptoms at admission and did not exhibit a significant overall change in symptoms over the course of treatment. More specifically, this second trajectory or "u-shaped responders" show a non-significant linear response through week four of treatment, followed by slightly increased symptoms in week five. Assignment to these classes was not differentially predicted by hypothesized predictor variables. LIMITATIONS: Our final model had inconsistent fit indices and small class prevalance of the u-shaped responder group; therefore, model selection was based on both fit indices and substantive meaning. CONCLUSIONS: This study emprically derived two distinct trajectories of OCD symptom severity over the course of IRT. These findings have the potential to refine IRT for patients with severe OCD, and to potentially guide future investigation into the optimal delivery of ERP treatment for OCD generally.


Assuntos
Transtornos Mentais/epidemiologia , Transtorno Obsessivo-Compulsivo/terapia , Tratamento Domiciliar/métodos , Adulto , Comorbidade , Feminino , Humanos , Masculino , Massachusetts/epidemiologia , Modelos Psicológicos , Transtorno Obsessivo-Compulsivo/epidemiologia , Qualidade de Vida , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
10.
J Behav Ther Exp Psychiatry ; 58: 114-122, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29111422

RESUMO

BACKGROUND AND OBJECTIVES: Repetitive negative thinking (RNT) is often associated with disruptions in sleep and circadian rhythms. Disruptions in sleep and circadian rhythms may deal a "second hit" to attentional control deficits. This study evaluated whether sleep and circadian rhythm disruptions are related to the top-down control of attention to negative stimuli in individuals with heightened repetitive negative thinking. METHODS: Fifty-two community adults with high levels of transdiagnostic RNT and varying habitual sleep durations and bedtimes participated in a hybrid free-viewing and directed attention task using pairs of emotionally-evocative and neutral images while eye-tracking data were collected. Self-report and clinician-administered interviews regarding sleep were also collected. RESULTS: Shorter habitual sleep duration was associated with more time looking at emotionally negative compared to neutral images during a free-viewing attention task and more difficulty disengaging attention from negative compared to neutral images during a directed attention task. In addition, longer sleep onset latencies were also associated with difficulty disengaging attention from negative stimuli. The relations between sleep and attention for positive images were not statistically significant. LIMITATIONS: A causal link between sleep and attentional control cannot be inferred from these cross-sectional data. The lack of a healthy control sample means that the relations between sleep disruption, attention, and emotional reactivity may not be unique to individuals with RNT. CONCLUSIONS: These findings suggest that sleep disruption may be associated with a specific impact on cognitive resources that are necessary for the top-down inhibitory control of attention to emotionally negative information.


Assuntos
Atenção/fisiologia , Pessimismo , Ruminação Cognitiva/fisiologia , Transtornos do Sono-Vigília/fisiopatologia , Sono/fisiologia , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
12.
J Behav Ther Exp Psychiatry ; 50: 23-32, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25989071

RESUMO

BACKGROUND AND OBJECTIVES: Obsessive-compulsive (OC) symptoms and repetitive negative thinking (RNT) are associated with poor inhibitory control. Sleep disruptions may partially mediate these relations and/or act as a "second hit" to individuals with OC symptoms and RNT. Models including habitual (past month) hours slept and bedtimes were tested. METHODS: We employed a go/no-go task that allowed us to examine the relation between sleep and inhibition with various task contingencies. Sixty-seven unselected individuals were recruited from the participant pool at a public university. RESULTS: Bias-corrected bootstrap estimates did not show that sleep disruption mediated the relation between OC symptoms and response inhibition nor the relation between RNT and response inhibition. Multiple linear regression analyses found significant interactions between hours slept and OC symptom severity and between RNT and hours slept to predict poor response inhibition. Hours slept significantly negatively predicted commission errors when OC symptoms and RNT levels were relatively heightened but not when OC symptoms and RNT levels were relatively low. These effects were present in blocks where task contingencies were designed to shape a no-go bias. No significant relations were found with habitual bedtimes. LIMITATIONS: The cross-sectional study design precludes testing the temporal precedence of symptoms in the "second hit" model. The unselected sample also limits generalization to clinical samples. CONCLUSIONS: These findings support a "second hit" model of interaction between sleep disruption and perseverative thoughts and behaviors. Further research on the mechanisms of the relation between sleep disruption and perseverative thought symptoms (OC and RNT) is warranted.


Assuntos
Inibição Psicológica , Transtorno Obsessivo-Compulsivo/fisiopatologia , Desempenho Psicomotor/fisiologia , Transtornos do Sono-Vigília/fisiopatologia , Pensamento/fisiologia , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
13.
Curr Psychiatry Rep ; 17(9): 73, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26216591

RESUMO

Anxiety is adaptive and plays an important role in keeping us safe. However, when anxiety becomes too extreme, it can cause significant disruptions and distress. Understanding the mechanisms underlying excessive anxiety and how to best treat it is a priority for researchers and clinicians. There is increasing recognition that disruptions in the amount and timing of sleep are associated with anxiety symptoms and characteristics. In the current paper, we explore the intersections between sleep, circadian rhythms, and anxiety. First, we review accumulating evidence that anxiety is associated with disruptions in sleep and circadian rhythms in both clinical and nonclinical samples and across ages. Next, we discuss the data linking sleep disruptions with anxiety-related traits (anxiety sensitivity, neuroticism, and perfectionism) and patterns of cognition and emotion. Finally, potential treatment implications are highlighted. Overall, these data suggest that delineating the role of disruptions in the amount and timing of sleep holds promise for improving the lives of individuals with heightened anxiety.


Assuntos
Adaptação Psicológica , Ansiedade/complicações , Ansiedade/etiologia , Ritmo Circadiano , Transtornos do Sono do Ritmo Circadiano/psicologia , Distúrbios do Início e da Manutenção do Sono/psicologia , Sono , Ansiedade/fisiopatologia , Transtornos de Ansiedade , Cognição , Emoções , Humanos , Neuroticismo
14.
Neurosci Biobehav Rev ; 51: 100-7, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25603315

RESUMO

Findings of this meta-analysis show that obsessive-compulsive disorder (OCD) is related to disruptions in both the duration and timing of sleep. PsycINFO and Google Scholar database searches identified 12 relevant studies that compared measures of sleep in individuals with OCD to those of either a healthy control group or published norms. Sleep measures included sleep onset latency, sleep duration, awakening after sleep onset, percentage of rapid eye movement (REM) sleep, percentage of slow wave sleep, and prevalence of delayed sleep phase disorder (DSPD). Individual effect sizes were pooled using a random effects model. Sleep duration was found to be shorter, and the prevalence of DSPD higher, in individuals with OCD compared to controls. Further, excluding samples with comorbid depression did not meaningfully reduce the magnitude of these effects (although the results were no longer statistically significant) and medication use by participants is unlikely to have systematically altered sleep timing. Overall, available data suggest that sleep disruption is associated with OCD but further research on both sleep duration and sleep timing in individuals with OCD is needed.


Assuntos
Nível de Alerta , Ritmo Circadiano , Transtorno Obsessivo-Compulsivo/fisiopatologia , Sono , Nível de Alerta/efeitos dos fármacos , Ritmo Circadiano/efeitos dos fármacos , Transtorno Depressivo/fisiopatologia , Humanos , Transtorno Obsessivo-Compulsivo/tratamento farmacológico , Psicotrópicos/uso terapêutico , Sono/efeitos dos fármacos
15.
Behav Cogn Psychother ; 43(4): 385-95, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24438479

RESUMO

BACKGROUND: Despite literature establishing a relationship between maladaptive beliefs and symptoms of obsessive-compulsive disorder (OCD), there are few studies addressing how these beliefs develop. Salkovskis and colleagues (1999) proposed specific domains of childhood experiences leading to heightened beliefs regarding responsibility. Prior studies in students and individuals who just completed treatment for OCD have found support for this theory. However, we are not aware of published data from individuals with current OCD. AIMS: This paper presents initial data from adults currently meeting criteria for OCD as well as both anxious and non-anxious controls. METHOD: Recollections of childhood experiences, current OCD-related beliefs, and OCD symptoms were assessed using self-report measures in 39 individuals seeking treatment for OCD, 36 anxious controls and 39 healthy controls. RESULTS: Initial data suggested that in individuals with OCD, increased reports of childhood exposure to overprotection and experiences where one's actions caused or influenced misfortune were associated with stronger OCD-related beliefs. Further, compared to community controls, individuals with OCD reported more childhood experiences where one's actions caused or influenced misfortune, though they did not differ from anxious controls in childhood responsibility experiences. CONCLUSIONS: These initial findings provide minimal support for the proposed model of the development of inflated responsibility beliefs, and highlight the need for research examining the etiology of OCD related beliefs with updated models, larger samples, and ultimately using prospective methods.


Assuntos
Transtorno Obsessivo-Compulsivo/etiologia , Transtorno Obsessivo-Compulsivo/psicologia , Desenvolvimento da Personalidade , Adulto , Estudos de Casos e Controles , Transtorno da Personalidade Compulsiva , Cultura , Feminino , Humanos , Masculino , Transtorno Obsessivo-Compulsivo/diagnóstico , Psicometria , Autorrelato , Transtornos do Comportamento Social/diagnóstico , Transtornos do Comportamento Social/psicologia , Inquéritos e Questionários
16.
J Cogn Psychother ; 28(2): 134-144, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-32759112

RESUMO

Deepening our understanding of the basic mechanisms underlying obsessive-compulsive disorder (OCD) often leads to advances in clinical practice. And, as noted by Kazdin (2008), clinical experiences are an important resource for identifying novel targets for empirical study. One potential target for furthering our understanding of OCD is to investigate clinical reports of within-day symptom fluctuations. Self-monitoring data from 17 adults with OCD were used to test for a diurnal pattern in obsessions. Results from generalized estimating equations revealed that obsessions were most common during midday and that the midday exacerbation was briefer in males. In combination with prior findings of similar diurnal patterns for other anxious symptoms (e.g., panic), these findings suggest that daily social rhythms and/or circadian influences may influence levels of obsessions. Furthermore, treatment may be improved by attending to these heightened symptom periods and integrating this information into therapy (e.g., when developing the exposure hierarchy).

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