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Mycoses ; 57(10): 639-43, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24980291

RESUMO

Cryptococcus gattii, a species belonging to the Cryptococcus complex which occurs endemically in tropical and subtropical regions, has been reported as a causative agent of cryptococcosis in healthy individuals. We report a case of meningitis in HIV-negative patient from Cuiaba, MT, in the Midwestern region of Brazil. Cryptococcus gattii AFLP6/VGII was isolated from cerebrospinal fluid and molecular typing was performed by URA5-RFLP. The in vitro susceptibility profile was determined using the standard method according to the document M27A3, CLSI 2008. C. gattii AFLP6/VGII was shown to be susceptible to the antifungals tested. Treatment with 0.8 mg/kg of amphotericin B was initiated; however, the patient died 2 days after the onset of therapy.


Assuntos
Criptococose/microbiologia , Cryptococcus gattii/isolamento & purificação , Meningite/microbiologia , Adulto , Antifúngicos/uso terapêutico , Brasil , Criança , Pré-Escolar , Criptococose/tratamento farmacológico , Cryptococcus gattii/efeitos dos fármacos , Cryptococcus gattii/genética , Evolução Fatal , Feminino , Genótipo , Humanos , Masculino , Meningite/tratamento farmacológico , Pessoa de Meia-Idade , Polimorfismo de Fragmento de Restrição
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