RESUMO
A patient with undiagnosed Ebola (EBO) hemorrhagic fever (EHF) was transferred from Kikwit to a private clinic in Kinshasa, Democratic Republic of the Congo. A diagnosis of EHF was suspected on clinical grounds and was confirmed by detection of EBO virus-specific IgM and IgG in serum of the patient. During the course of the disease, although she had no known predisposing factors, the patient developed a periorbital mucormycosis abscess on eyelid tissue that was biopsied during surgical drainage; the abscess was histologically confirmed. Presence of EBO antigen was also detected by specific immunohistochemistry on the biopsied tissue. The patient survived the EBO infection but had severe sequelae associated with the mucormycosis. Standard barrier-nursing precautions were taken upon admission and upgraded when EHF was suspected; there was no secondary transmission of the disease.
Assuntos
Doença pelo Vírus Ebola/complicações , Mucormicose/complicações , Adulto , Anticorpos Antivirais/sangue , Antígenos Virais/metabolismo , Cegueira/etiologia , República Democrática do Congo , Ebolavirus/imunologia , Ebolavirus/isolamento & purificação , Doenças Palpebrais/complicações , Doenças Palpebrais/microbiologia , Doenças Palpebrais/virologia , Feminino , Doença pelo Vírus Ebola/diagnóstico , Doença pelo Vírus Ebola/virologia , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Mucormicose/microbiologia , Mucormicose/virologia , Infecções Oportunistas/complicações , Infecções Oportunistas/microbiologia , Infecções Oportunistas/virologiaRESUMO
A partir d'une etude retrospective; les auteurs analysent les causes antenatales et perinatales des hemorragies cerebrales intraventriculaires survenues chez 49 nouveaux-nes a terme. Il en ressort que seules les anomalies d'accouchement jouent vraisemblement un role significatif dans le declenchement de cette pathologie et que d'autre part un score d'Apgar excellent n'a aucune valeur predictive sur l'eclosion de cette maladie
