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J Agric Food Chem ; 61(46): 10981-6, 2013 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-24164385

RESUMO

Nopal (Opuntia ficus-indica) cladodes are recommended for their therapeutic properties; their maturity stage may affect their biological properties. Cladodes of three maturity stages, from the same crop and location, were dehydrated and evaluated for some of their physicochemical and nutritional characteristics and antidiabetic properties. The flours of small and medium cladodes (SCF and MCF, respectively) had higher contents of dietary fiber, water absorption, swelling, and viscosity compared to those of the large cladode flour (LCF). Streptozotocin-induced diabetic rats, treated with MCF and SCF (doses of 50 mg/kg body weight), showed reduction of postprandial blood glucose on 46.0 and 23.6%, respectively (p < 0.05), in relation to the control; and LCF had no significant effect. In vitro, glucose diffusion tests showed similar ranking by the two former samples, whereas the latter was close to the control. Cladode maturity stages showed different fiber content and produced suspensions with differences in viscosity, which may affect in vitro and in vivo glucose responses.


Assuntos
Diabetes Mellitus/tratamento farmacológico , Hipoglicemiantes/administração & dosagem , Opuntia/química , Extratos Vegetais/administração & dosagem , Caules de Planta/química , Animais , Glicemia/metabolismo , Diabetes Mellitus/metabolismo , Humanos , Hipoglicemiantes/química , Masculino , Opuntia/crescimento & desenvolvimento , Extratos Vegetais/química , Caules de Planta/crescimento & desenvolvimento , Ratos , Ratos Wistar
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